Results 41 to 50 of about 2,691 (173)

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao, Yinkai Yang, Tiantian Chen, Xiaoxuan Fan, Yiqing Peng, Qingyan Ruan, Qin Zhou, Fanghao Liu, Jiayi He, Yongpeng Li, Yue Feng, Jiyan Qi, Guoyin Kai   +12 more
wiley   +1 more source

Catharanthus roseus intoxication mimicking acute cholangitis

BMC Complementary Medicine and Therapies
Background Catharanthus roseus, a Madagascar native flowering plant, is known for its glossy leaves and vibrant flowers, and its medicinal significance due to its alkaloid compounds.
Yoen Young Chuah, Yeong Yeh Lee, Chu-Kuang Chou, Li-Jen Chang   +3 more
doaj   +1 more source

Ointment Formulation of Tapak Dara Flower (Catharanthus roseus (L.) G. Don) Ethanol Extract and its Activity in Burn-Healing

Borneo Journal of Pharmacy, 2023
Treatment done on burn wounds is intended to provide local therapy to heal as quickly as possible. The content of secondary metabolites in the Tapak Dara (Catharanthus roseus (L.) G.
Leny Leny, Tetty Noverita Khairani Situmorang, Rensus Siagian, Ihsanul Hafiz, Benni Iskandar   +4 more
doaj   +1 more source

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang, Xing Wu, Maria Moreno, Joonseok Oh, Stephen L. Dellaporta, Jason M. Crawford, Farren J. Isaacs   +6 more
wiley   +1 more source

Anticancer activityof alkaloids of Madagascar Periwinkle Catharanthusroseus (L.)G.Don against two cancer cell line

مجلة علوم ذي قار, 2019
In the present study , Madagascar Periwinkle Catharanthus roseus (L.)G.Don alkaloids were evaluated against two cancer cell lines :larynx human cancer cell line Hep2,and mouse breast cancer cell line AMN3 , by using four  concentrations for each cell ...
Ali Shareef
doaj   +4 more sources

Phytochemical profiling and antioxidant potentiality of medicinal plants along with their antibacterial efficacy

Journal of Advanced Biotechnology and Experimental Therapeutics, 2019
The leaves of Catharanthus roseus, Aegle marmelos, Moringa oleifera, Ageratum conyzoids, collected from Sylhet region in Bangladesh, were extracted using methanol with an aim to investigate antioxidant potential and antibacterial activity.
Sheikh Rashel Ahmed, Ismat Jahan Romi, Jamil Ahmed, Mahmudul Hasan, Rubel Roy, Mohammad Mehedi Hasan Khan   +5 more
doaj   +1 more source

Chitosan‐induced modulation of secondary metabolism and stress tolerance in Salvia rosmarinus under combined drought and heat stress

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5989-6001, 15 August 2026.
Abstract BACKGROUND Abiotic stresses, particularly drought and elevated temperatures, negatively affect plant physiological and metabolic processes. This study investigated the effects of drought, heat, and combined stress on Salvia rosmarinus (rosemary), and evaluated foliar‐applied chitosan as a biostimulant.
Inês Mansinhos, Sandra Gonçalves, Raquel Rodríguez‐Solana, Efrén Pérez‐Santín, María I Fernández‐Marín, Emma Cantos‐Villar, Anabela Romano   +6 more
wiley   +1 more source

Plant‐Derived Nanoparticles (PDNPs) in Food Safety and Preservation: Pros and Cons

eFood, Volume 7, Issue 4, August 2026.
Plant‐derived nanoparticles (PDNPs) synthesized via green methods demonstrate antimicrobial, antioxidant, barrier, eco‐friendly, and cost‐effective properties, while facing challenges in large‐scale production, synthesis standardization, and absence of specific food safety regulations. ABSTRACT Ensuring food safety and extending shelf life across fresh
Md. Shakil Ahmed, M. Mahadi Hasan, Most. Zakia Yeasmin   +2 more
wiley   +1 more source

Cross‐stage single‐cell and spatial metabolome analyses reveal periderm specialization and tanshinone biosynthesis in Salvia miltiorrhiza roots

New Phytologist, Volume 251, Issue 3, Page 1267-1282, August 2026.
Biosynthesis and accumulation of tanshinones in the periderm of Salvia miltiorrhiza during secondary root growth. Summary Perennial herbs develop long‐lived roots that undergo repeated cycles of secondary growth, during which the periderm functions as a protective barrier and a major site of specialized metabolite accumulation.
Licheng Liu, Lianchong Gao, Zhi‐Ying Wang, Yan Liu, Huifeng Ju, Huana Lin, Zheng Shi, Wen‐Juan Cai, Xue Li, Yan‐Bo Huang, Yu Kong, Jing‐Jing Xu, Hong‐Peng Chen, Xin Fang, Juan Guo, Yong‐Hong Hu, Ke Chen, Xiao‐Ya Chen, Jie Hao, Lei Yang   +19 more
wiley   +1 more source

Silver Nanoparticles Green Synthesis from Catharanthus roseus Flowers and Effect on A549 Lung Cancer Cells

Brazilian Archives of Biology and Technology, 2023
Silver nanoparticles (AgNPs) have extensive applications in nanomedicine due to their physicochemical properties and interactions with biomolecules. One way of obtaining them is through green synthesis with plant extracts containing reducing and capping ...
Marcela Novak Gumy, Carla Cristine Kanunfre, Josiane de Paula Padilha, Luíza Stolz Cruz, Patrícia Mathias Döll Boscardin   +4 more
doaj   +1 more source