Results 31 to 40 of about 2,691 (173)

De Novo transcriptome assembly and differential expression analysis of catharanthus roseus in response to salicylic acid

Scientific Reports, 2022
The anti-cancer vinblastine and vincristine alkaloids can only be naturally found in periwinkle (Catharanthus roseus). Both of these alkaloids' accumulations are known to be influenced by salicylic acid (SA).
Narges Soltani, Farhad Nazarian Firouzabadi, Alireza Shafeinia, Masoud Shirali, Ayeh Sadat Sadr   +4 more
doaj   +1 more source

Do Fungicides Affect Alkaloid Production in Catharanthus roseus (L.) G. Don. Seedlings?

Molecules, 2023
The presence of endophytes in plants is undeniable, but how significant their involvement is in the host plant biosynthetic pathways is still unclear. The results reported from fungicide treatments in plants varied. Fungicide treatment in Taxus was found
Purin Candra Purnama, Leonardo Castellanos Hernandez, Robert Verpoorte   +2 more
doaj   +1 more source

Cryopreservation of Alkaloid-Producing Cell Cultures of Periwinkle (Catharanthus roseus) [PDF]

Plant Physiology, 1984
A procedure for cryogenic storage of alkaloid producing cell lines of periwinkle, Catharanthus roseus (L.) G. Don., has been developed. The procedure differs from established cryopreservation protocols in several aspects. Specifically, 4-day-old suspension subcultures of three cell lines were precultured in nutrient media supplemented with 1 molar ...
Chen, Tony H. H., Kartha, Kutty K., Leung, Nicholas L., Kurz, Wolfgang G. W., Chatson, Kenneth B., Constabel, Friedrich   +5 more
openaire   +2 more sources

Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics. [PDF]

PLoS ONE, 2012
In order to improve the production of the anticancer dimeric indole alkaloids in Catharanthuse roseus, much research has been dedicated to culturing cell lines, hairy roots, and efforts to elucidate the regulation of the monoterpenoid indole alkaloid ...
Qifang Pan, Quan Wang, Fang Yuan, Shihai Xing, Jingya Zhao, Young Hae Choi, Robert Verpoorte, Yuesheng Tian, Guofeng Wang, Kexuan Tang   +9 more
doaj   +1 more source

Eliciting Effect of Catharanthine on the Biosynthesis of Vallesiachotamine and Isovallesiachotamine in Cambial Meristematic Cells

Natural Product Communications, 2018
Vallesiachotamine and isovallesiachotamine are pharmacologically active monoterpene indole alkaloids produced by Catharanthus roseus . However, the biosynthetic pathway for these two alkaloids has not been characterized.
Jianhua Zhu, Shuijie He, Pengfei Zhou, Jiachen Zi, Jincai Liang, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source

Boosting of Antioxidants and Alkaloids in Catharanthus roseus Suspension Cultures Using Silver Nanoparticles with Expression of CrMPK3 and STR Genes

Plants, 2021
Global agricultural systems are under unprecedented pressures due to climate change. Advanced nano-engineering can help increase crop yields while ensuring sustainability. Nanotechnology improves agricultural productivity by boosting input efficiency and
Ahmed Fouad, Adel E. Hegazy, Ehab Azab, Ebtihal Khojah, Tarek Kapiel   +4 more
doaj   +1 more source

Crystal structure of akuammicine, an indole alkaloid fromCatharanthus roseus [PDF]

Acta Crystallographica Section E Crystallographic Communications, 2017
The title compound, C20H22N2O2, an alkaloid isolated from the Madagascar periwinkle, crystallizes inP1 with two independent but closely similar molecules in the unit cell. The molecules are linked into pairs by two N—H...O=C hydrogen bonds. The absolute configuration was confirmed by anomalous dispersion effects asSat the 3 and 15 positions, andRat the
Yahyazadeh, Mahdi, Jerz, Gerold, Selmar, Dirk, Winterhalter, Peter, Jones, Peter G.   +4 more
openaire   +4 more sources

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie International Edition, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

Pharmacological significance of Catharanthus roseus in cancer management: A review

Pharmacological Research - Modern Chinese Medicine
Introduction: Catharanthus roseus, commonly known as Vinca Rosea or Madagascar periwinkle, is a significant plant species within the Apocynaceae family, known for its diverse medicinal properties and ornamental attributes, long embraced by Chinese ...
Siddharth Goswami, Amena Ali, Madhulika Esther Prasad, Pallavi Singh   +3 more
doaj   +1 more source