Results 21 to 30 of about 134,369 (196)

Indole Alkaloids from Catharanthus roseus: Bioproduction and Their Effect on Human Health

open access: yesMolecules, 2015
Catharanthus roseus is a medicinal plant belonging to the family Apocynaceae which produces terpenoid indole alkaloids (TIAs) of high medicinal importance.
Lorena Almagro   +2 more
doaj   +1 more source

BHLH IRIDOID SYNTHESIS 3 is a member of a bHLH gene cluster regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus

open access: yesPlant Direct, 2021
Basic helix‐loop‐helix (bHLH) transcription factors (TFs) are key regulators of plant specialized metabolites, including terpenoid indole alkaloids (TIAs) in Catharanthus roseus.
Sanjay Kumar Singh   +5 more
doaj   +1 more source

Metabolomic responses to the mechanical wounding of Catharanthus roseus’ upper leaves [PDF]

open access: yesPeerJ, 2023
Purpose Plant secondary metabolites are used to treat various human diseases. However, it is difficult to produce a large number of specific metabolites, which largely limits their medicinal applications.
Qi Chen   +6 more
doaj   +2 more sources

Repression of ZCT1, ZCT2 and ZCT3 affects expression of terpenoid indole alkaloid biosynthetic and regulatory genes [PDF]

open access: yesPeerJ, 2021
Terpenoid indole alkaloids (TIAs) include several valuable pharmaceuticals. As Catharanthus roseus remains the primary source of these TIA pharmaceuticals, several research groups have devoted substantial efforts to increase production of these compounds
Chun Yao Li, Susan I. Gibson
doaj   +2 more sources

Chromium-induced alkaloid production in Catharanthus roseus (L.) G.Don in vitro cultured shoots and related gene expression patterns particularly for the novel gene GS

open access: yesActa Agriculturae Slovenica, 2019
This study aimed to determine the effects of methyl jasmonate (Mj) combined with chromium (Cr) as elicitor on production of medicinal alkaloids, its antioxidant potential, and its effects on the expression of signaling and biosynthetic enzymes.
Elham KHATAEE   +2 more
doaj   +1 more source

Antiplasmodial Bis-Indole Alkaloids from the Bark of Flindersia pimenteliana

open access: yes, 2020
Three new (1-3) and 2 known (4-5) bis-indole alkaloids were identified from the bark of Flindersia pimenteliana (Rutaceae). The structures of 1-3 were elucidated on the basis of their (+)-HRESESIMS and 2D NMR spectroscopic data.
Lucantoni, Leonardo   +3 more
core   +1 more source

Biosynthesis of fungal indole alkaloids [PDF]

open access: yes, 2014
This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to incorporate and derivatize the indole/indoline moieties in various families of fungal indole alkaloids
Gavia, Diego J   +5 more
core   +1 more source

Marine indole alkaloids [PDF]

open access: yes, 2015
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development.
Opatz, Till, Netz, Natalie
core   +2 more sources

Silencing the Transcriptional Repressor, ZCT1, Illustrates the Tight Regulation of Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus Hairy Roots. [PDF]

open access: yesPLoS ONE, 2016
The Catharanthus roseus plant is the source of many valuable terpenoid indole alkaloids (TIAs), including the anticancer compounds vinblastine and vincristine.
Noreen F Rizvi   +3 more
doaj   +1 more source

Changing in the production of anticancer drugs (vinblastine and vincristine) in Catharanthus roseus (L.) G. Don by potassium and ascorbic acid treatments

open access: yesPlant, Soil and Environment, 2022
Catharanthus roseus seedling was treated with different concentrations (1.5, 3.16, 15, and 30 mmol) and forms (K2SO4 and KNO3) of potassium (K+) via Hoagland's nutrient solution. Ascorbic acid (AsA) was sprayed twice (plant days 68 and 78) with different
Neda Sahi   +2 more
doaj   +1 more source

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