Results 21 to 30 of about 31,171 (226)

Discovery of active site of vinblastine as application of nanotechnology in medicine [PDF]

Nanomedicine Journal, 2014
Objective(s): Vinblastine is antimitotic, anticancer medicine that disturbs normal microtubule formation and favours depolymerisation. Structural study and finding the active site of vinblastine are the targets of this research.
Zahra varmaghani, Majjid Monajjemi, Fatemeh mollaamin   +2 more
doaj  

Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus

Plants, 2021
Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of
Tran My Linh, Nguyen Chi Mai, Pham Thi Hoe, Ninh Thi Ngoc, Phan Thi Hong Thao, Ninh Khac Ban, Nguyen Tuong Van   +6 more
doaj   +1 more source

Vinblastine-induced autophagocytosis: effects on liver glycogen [PDF]

, 1983
The possible similarities of the mechanism by which vinblastine induces autophagocytosis in liver were compared with the known effects of glucagon in glucagon-induced autophagocytosis.
Pirrko Hirsimäki, Hirsimäki, Pirrko
core   +1 more source

Vinblastine in Children and Adolescents With High-Risk Anaplastic Large-Cell Lymphoma: Results of the Randomized ALCL99-Vinblastine Trial

, 2010
Purpose The impact of adding vinblastine to a 4-month chemotherapy regimen, based on the Non- Hodgkin’s Lymphoma Berlin-Frankfurt-Mu ̈ nster 90 protocol, in childhood high-risk anaplastic large-cell lymphoma (ALCL) was assessed.
Le Deley, Marie-Cécile, WOESSMANN W, ATTARBASCHI A, Uyttebroeck, Anne, PILLON M, BRUGIERES L., WILLIAMS DM, MAUGUEN A, LAMANT L, ROSOLEN, ANGELO, HORIBE K, HOBSON R, Woessmann, Wilhelm, Reiter, Alfred, Williams, Denise M., Marky, Ildiko M., Wrobel, Grazyna, WROBEL G, REITER A, Zsiros, Jozsef, Brugières, Laurence, UYTTEBROECK A, Horibe, Keizo, Mauguen, Audrey, Attarbaschi, Andishe, Pillon, Marta, ZSIROS J, Lamant, Laurence, Hobson, Rachel, MARKY IM, LE DELEY MC   +30 more
core   +2 more sources

CELL CARRIERS AS SYSTEMS OF DELIVERY OF ANTITUMOR DRUGS (REVIEW)

Разработка и регистрация лекарственных средств, 2019
Introduction. Drug delivery systems are defined as systems that deliver the optimal amount of a drug to a target target, increase the effectiveness of treatment, and reduce adverse effects.
O. V. Trineeva, A. J. Halahakoon, A. I. Slivkin   +2 more
doaj   +1 more source

Clinical and immunohistochemical findings of splenic mast cell tumour in a cat: A case report

Veterinární Medicína, 2021
A 6-year-old, spayed, female, domestic shorthair cat presented with a 4-month history of chronic intermittent vomiting and anorexia. The haematologic results indicated moderate anaemia and a circulating mast cell population.
S Lee, Kang MS, Y Jeong, Y Kim, Kwak HH, Choi EW, S Choi, I Park, Chung JY, Choi JH, Ahn JO   +10 more
doaj   +1 more source

Study of Desorbtion and Exemption of Terpeno-indole Alkaloids of Vinkristin and Vinblastin from Erythrocitary Cell Carriers

Разработка и регистрация лекарственных средств, 2019
Introduction. Employees of the Department of Pharmaceutical Chemistry and Pharmaceutical Technology have obtained modified forms of terpino-indole alkaloids (ТIA) and vinbristine (VCR) and vinblastine (VBL) known in the treatment of cancer diseases by ...
O. V. Trineeva, A. D. Khalahakun
doaj   +1 more source

Catharanthus roseus (L.) G. Don - plant regeneration and alkaloids content

Acta Societatis Botanicorum Poloniae, 2014
We describe here a regeneration of plantlets of Catharanthus roseus (L.) G. Don from shoot tips and axillary buds. Shoot tips were excised from 7-day-old seedlings and were incubated in solid Nitsch and Nitsch (NN) medium supplemented with kinetin ...
Mirosława Furmanowa, Hanna Olędzka, Joanna Józefowicz, Agnieszka Pietrosiuk   +3 more
doaj   +1 more source

Stereocontrolled Total Synthesis of (+)-Vinblastine

, 2016
A stereocontrolled total synthesis of (+)-vinblastine was accomplished, featuring preparations of the two indole units by means of a novel indole synthesis via radical cyclization of thioanilide, and a stereoselective coupling of these ...
Satoshi Kobayashi (700034), Takeshi Kuboyama (2987859), Tohru Fukuyama (1508317), Hidetoshi Tokuyama (1748674), Satoshi Yokoshima (1575334), Ayato Sato (2987856), Toshihiro Ueda (2987853)   +6 more
core   +1 more source

Vinblastine-Type Antitumor Alkaloids:  A Method for Creating New C17 Modified Analogues

, 2016
Vinblastine-Type Antitumor Alkaloids:  A Method for Creating New C17 Modified ...
Alessandra Silvani (1493923), Marisa Martinelli (2377567), Mai Ngoc Tam (3045888), Daniele Passarella (129791), Bruno Danieli (2643796), Giordano Lesma (1493932), Bogomil Pyuskyulev (3045885)   +6 more
core   +1 more source