Results 171 to 180 of about 77,793 (276)

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

Movement Disorders, Volume 41, Issue 6, Page 1516-1527, June 2026.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes, Adriana Marcelo, Ana Teresa Rajado, Rafael G. Costa, Ricardo Afonso‐Reis, Cristiana R. Madeira, Inês T. Afonso, David V.C. Brito, Adriana A. Vaz, Clévio Nóbrega   +9 more
wiley   +1 more source

Automated Classification of Homeostasis Structure in Input-Output Networks. [PDF]

Bull Math Biol
Lin X, Antoneli F, Wang Y.
europepmc   +1 more source

Genome Mining Approaches for Toxicant Discovery: A Case Study Examining Receptor Proteins for Pest Management in New Zealand

New Zealand Journal of Zoology, Volume 53, Issue 2, June 2026.
Pest control is a global challenge for agriculture and biodiversity conservation, with the use of existing vertebrate pesticides increasingly constrained by regulatory, environmental, and social pressures. There is an urgent need for safer and more species‐selective toxicants, but the development of novel vertebrate pesticides remains technically ...
Erica R. Hendrikse, Natalie J. Forsdick, Wanting Jiao, Brian Hopkins   +3 more
wiley   +1 more source

Propafenone Toxicity Presenting With Wide QRS and Transient Ventricular Dyskinesia. [PDF]

JACC Case Rep
Araújo de Lucena L, da Costa Fernandes Mesquita F, Rigon Madeira M, Saraiva da Silva Maia FG.   +3 more
europepmc   +1 more source

Sequence and structural alignments reveal insights into ANKLE2 evolution and function

Protein Science, Volume 35, Issue 6, June 2026.
Abstract ANKLE2 is an enigmatic protein with emerging roles in cell division, development, and virus replication. While ANKLE2 orthologs are present in all animals, its domain composition has evolved over time. ANKLE2's two namesake domains, the ankyrin repeat and LEM domains (named for LAP2, Emerin, and MAN1), have clear and defined roles; however ...
Adam T. Fishburn, Cole J. Florio, Chase L. S. Skawinski, Sydney S. Becker, Ethan Holleman, Avery E. Robertson, Rees Sitchon, Frédéric Chédin, Priya S. Shah   +8 more
wiley   +1 more source

High-resolution regional climate projections and tourism impacts in the Macaronesian archipelagos. [PDF]

Sci Rep
Rodríguez-Rull J, Expósito FJ, Díaz JP, Carrillo J, Pérez JC, Henriques D.   +5 more
europepmc   +1 more source

Plurilinguismo na Universidade da Madeira: um caso de multiculturalismo

, 2008
Tem-se verificado que o corpo docente da Universidade da Madeira (UMa) é cada vez mais heterogéneo. Nesta universidade periférica, cruzam-se professores com realidades culturais distintas porque provenientes dos quatro cantos do mundo.
Moniz, Ana Isabel
core  

Functional thermodynamics govern the ligand binding to human cytosolic transport proteins

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Traditional binding studies on cellular, molecular transporters often simplify the thermodynamics of binding processes. We present a method that combines spin probing, electron paramagnetic resonance (EPR) spectroscopy and spectral simulations with binding studies and thermodynamics for an in‐depth molecular view into ligand binding and ...
Sebastian Michler, Christian Schwieger, Florian Arndt Schöffmann, Dariush Hinderberger   +3 more
wiley   +1 more source

Risk factors and outcomes of healthcare-associated infections in a Brazilian intensive care unit: A cross-sectional study. [PDF]

Belitung Nurs J
de Sousa Moura AM, de Sousa ÁFL, de Carvalho HEF, Madeira MZA, Freitas DRJ, Lima ACM, Carneiro LM, Valim MD, Junior AGDS, Batista OMA.   +9 more
europepmc   +1 more source

The liverwort genus Metzgeria (Jungermanniopsida) in Europe – An integrative taxonomic update

TAXON, Volume 75, Issue 3, June 2026.
Abstract Species delimitation in liverworts, such as Metzgeria, is hampered by their limited morphology and hence morphologically determined specimens often turn out to belong to other taxa using molecular data. Metzgeria is a simple thalloid liverwort genus with over 100 species and a worldwide distribution. Seven species are listed to occur in Europe.
Julia Bechteler, Alfons Schäfer‐Verwimp, Dietmar Quandt, Martin Nebel   +3 more
wiley   +1 more source