Results 1 to 10 of about 50,157 (93)

Implication of diabetes mellitus in telomere length and alteration in some age related cell senescence markers of aged men in Kurdistan region-Iraq

Kurdistan Journal of Applied Research, 2022
Indications of cell maturing including telomere length and mitochondrial work, just as oxidative pressure and incendiary markers affect one another and structure a complicated organization, which all influenced in age related sicknesses, for ...
Kaniaw Rafat Khafar, Dr. Esmail S Kakey
doaj   +48 more sources

Adverse events in both childhood and adulthood are associated with molecular, clinical and functional markers of ageing [PDF]

BMC Medicine
Background Adverse events across the lifespan have been linked to poorer health outcomes, but the biological mechanisms remain unclear. The aim of this study was to quantify the independent and joint associations of adversity experienced in childhood and/
Monica Aas, Thole H Hoppen, Nexhmedin Morina, Shiyu Zhang, Bin Li, Vid Mlakar, Julian Mutz   +6 more
doaj   +2 more sources

Psychological distress in older adults: associations with epigenetic markers of ageing, inflammation, and depression, and joint effects on mortality

Brain, Behavior, & Immunity - Health
Background: Psychological distress is associated with adverse health outcomes. We aimed to assess whether the health impacts of psychological distress could be captured by epigenetic markers of ageing, inflammation, and depression, and whether these ...
Danmeng Lily Li, Xiaojing Xu, Allison M. Hodge, Melissa C. Southey, Graham G. Giles, Roger L. Milne, Pierre-Antoine Dugué   +6 more
doaj   +3 more sources

An approach of the Madeira Wine Chemistry

Beverages, 2020
Madeira wine is a fortified Portuguese wine, which has a crucial impact on the Madeira Island economy. The particular properties of Madeira wine result from the unique and specific winemaking and ageing processes that promote the occurrence of chemical ...
Rosa Perestrelo, Catarina Silva, Carolina Gonçalves, Mariangie Castillo, José S. Câmara   +4 more
doaj   +1 more source

Immune Clearance of Senescent Cells to Combat Ageing and Chronic Diseases

Cells, 2020
Senescent cells are generally characterized by permanent cell cycle arrest, metabolic alteration and activation, and apoptotic resistance in multiple organs due to various stressors.
Ping Song, Junqing An, Ming-Hui Zou
doaj   +1 more source

Red Wine Oxidation: Accelerated Ageing Tests, Possible Reaction Mechanisms and Application to Syrah Red Wines

Antioxidants, 2020
Wine oxidation and ageing involve many complex chemical pathways and reaction mechanisms. The purpose of this study is to set up new and reproducible accelerated red wine ageing tests and identify chemical oxidation or ageing molecular markers.
Stacy Deshaies, Guillaume Cazals, Christine Enjalbal, Thibaut Constantin, François Garcia, Laetitia Mouls, Cédric Saucier   +6 more
doaj   +1 more source

Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

Stem Cell Research & Therapy, 2020
Introduction This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added.
Juan Fafián-Labora, Miriam Morente-López, María José Sánchez-Dopico, Onno J. Arntz, Fons A. J. van de Loo, Javier De Toro, María C. Arufe   +6 more
doaj   +1 more source

Assessment of Physiological Rat Kidney Ageing—Implications for the Evaluation of Allograft Quality Prior to Renal Transplantation

Metabolites, 2022
Due to organ shortage and rising life expectancy the age of organ donors and recipients is increasing. Reliable biomarkers of organ quality that predict successful long-term transplantation outcomes are poorly defined.
Andreas Baumgartner, Simone Reichelt-Wurm, Wolfram Gronwald, Claudia Samol, Josef A. Schröder, Claudia Fellner, Kathrin Holler, Andreas Steege, Franz Josef Putz, Peter J. Oefner, Bernhard Banas, Miriam C. Banas   +11 more
doaj   +1 more source

Fat and carbohydrate intake over three generations modify growth, metabolism and cardiovascular phenotype in female mice in an age-related manner. [PDF]

PLoS ONE, 2015
Environmental challenges such as a high fat diet during pregnancy can induce changes in offspring growth, metabolism and cardiovascular function.
Samuel P Hoile, Leonie R Grenfell, Mark A Hanson, Karen A Lillycrop, Graham C Burdge   +4 more
doaj   +1 more source

Inflammatory marker trajectories associated with frailty and ageing in a 20‐year longitudinal study

Clinical & Translational Immunology, 2022
Objective The aim of this exploratory study was to investigate the development of low‐grade inflammation during ageing and its relationship with frailty.
Leonard Daniël Samson, Anne‐Marie Buisman, José A Ferreira, H Susan J Picavet, W M Monique Verschuren, Annemieke MH Boots, Peter Engelfriet   +6 more
doaj   +1 more source