Results 1 to 10 of about 52,982 (221)

Adverse events in both childhood and adulthood are associated with molecular, clinical and functional markers of ageing [PDF]

open access: yesBMC Medicine
Background Adverse events across the lifespan have been linked to poorer health outcomes, but the biological mechanisms remain unclear. The aim of this study was to quantify the independent and joint associations of adversity experienced in childhood and/
Monica Aas   +6 more
doaj   +2 more sources

Immune Clearance of Senescent Cells to Combat Ageing and Chronic Diseases

open access: yesCells, 2020
Senescent cells are generally characterized by permanent cell cycle arrest, metabolic alteration and activation, and apoptotic resistance in multiple organs due to various stressors.
Ping Song, Junqing An, Ming-Hui Zou
doaj   +1 more source

An approach of the Madeira Wine Chemistry

open access: yesBeverages, 2020
Madeira wine is a fortified Portuguese wine, which has a crucial impact on the Madeira Island economy. The particular properties of Madeira wine result from the unique and specific winemaking and ageing processes that promote the occurrence of chemical ...
Rosa Perestrelo   +4 more
doaj   +1 more source

Red Wine Oxidation: Accelerated Ageing Tests, Possible Reaction Mechanisms and Application to Syrah Red Wines

open access: yesAntioxidants, 2020
Wine oxidation and ageing involve many complex chemical pathways and reaction mechanisms. The purpose of this study is to set up new and reproducible accelerated red wine ageing tests and identify chemical oxidation or ageing molecular markers.
Stacy Deshaies   +6 more
doaj   +1 more source

The Role of BDNF on Aging-Modulation Markers [PDF]

open access: yesBrain Sciences, 2020
An important link between brain aging and a class of growth/survival factors called neurotrophins has recently been demonstrated. In particular, brain-derived neurotrophic factor (BDNF) plays a fundamental role during age-related synaptic loss, preventing cerebral atrophy and cognitive decline.
Molinari C.   +6 more
openaire   +4 more sources

Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

open access: yesStem Cell Research & Therapy, 2020
Introduction This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added.
Juan Fafián-Labora   +6 more
doaj   +1 more source

Endocrine markers of aging [PDF]

open access: yesExperimental Gerontology, 1988
Sophisticated methods available to quantitate hormone secretion and hormone action provide opportunities to identify potential endocrine biomarkers of aging. However, there are many challenges facing the investigator who wishes to establish an endocrine biomarker.
openaire   +3 more sources

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age [PDF]

open access: yesThe Journal of Prevention of Alzheimer's Disease, 2020
The Geroscience aims at a better understanding of the biological processes of aging, to prevent and/or delay the onset of chronic diseases and disability as well as to reduce the severity of these adverse clinical outcomes. Geroscience thus open up new perspectives of care to live a healthy aging, that is to say without dependency.
Guerville, Florent   +14 more
openaire   +5 more sources

Metabolomics in aging research: aging markers from organs

open access: yesFrontiers in Cell and Developmental Biology, 2023
Metabolism plays an important role in regulating aging at several levels, and metabolic reprogramming is the main driving force of aging. Due to the different metabolic needs of different tissues, the change trend of metabolites during aging in different organs and the influence of different levels of metabolites on organ function are also different ...
Weicheng Fang   +6 more
openaire   +3 more sources

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