Results 41 to 50 of about 50,207 (142)

Age‐related changes of oxidative status and immune function in a long‐lived seabird

Journal of Avian Biology
Experimental studies in humans and laboratory species have shown that the decline of the immune system with age (immunosenescence) and the accumulation of oxidative damage to macromolecules are two key contributors to the onset and progression of the ...
Beatrice Berardi, Giacomo Dell'Omo, Gianluca Damiani, Gábor Á. Czirják, Silvia Filippi, Claudio Carere, David Costantini   +6 more
doaj   +1 more source

Establishment of an induced pluripotent cell line (ABCRIi001-A) from an elderly female for ageing research

Stem Cell Research
Human induced pluripotent stem cells (hiPSCs) hold promises to model and understand human diseases, including those associated with ageing. Here, we describe ABCRIi001-A, a hiPSC line generated from peripheral blood mononuclear cells (PBMCs) of a 79-year-
Filipa Esteves, David Brito, Ana Teresa Rajado, Nádia Silva, Joana Apolónio, Vânia Palma Roberto, Raquel P. Andrade, Sofia Calado, Maria Leonor Faleiro, Carlos Matos, Nuno Marques, Ana Marreiros, Hipólito Nzwalo, Sandra Pais, Isabel Palmeirim, Sónia Simãoa, Natércia Joaquim, Rui Miranda, António Pêgas, Daniela Marques Raposo, Ana Sardo, Inês Araújo, Clévio Nóbrega, Pedro Castelo-Branco, José Bragança   +24 more
doaj   +1 more source

Transcriptomic Profile of Mouse Brain Ageing in Early Developmental Stages

Brain Sciences
Ageing is a continuous process that can cause neurodevelopmental changes in the body. Several studies have examined its effects, but few have focused on how time affects biological processes in the early stages of brain development.
Karolina Kulis, Kevin Tabury, Mohammed Abderrafi Benotmane, Joanna Polanska   +3 more
doaj   +1 more source

GNF-5837 alleviates intervertebral disc ageing by upregulating glutathione peroxidase 7

International Journal of Immunopathology and Pharmacology
Objective: The aim of this study was to investigate the role of glutathione peroxidase 7 (GPX7) in mitigating oxidative stress-induced cellular ageing and its contribution to intervertebral disc degeneration (IVDD).
Yangkai Xu, Rongsheng Chen, Yan Zhuang, Weihong Xu   +3 more
doaj   +1 more source

Red blood cells ageing markers: a multi-parametric analysis. [PDF]

Blood Transfus, 2017
Bardyn M, Rappaz B, Jaferzadeh K, Crettaz D, Tissot JD, Moon I, Turcatti G, Lion N, Prudent M.   +8 more
europepmc   +1 more source

Mid- and late-life cardiovascular health indicators and changes in biological ageing Markers; a multi-cohort study. [PDF]

EBioMedicine
Asefa NG, Hu YH, Li Z, Zheng Y, Meirelles O, Romero JM, Lloyd-Jones DM, Kuo PL, Gudmundsdottir V, Tanaka T, Aspelund T, Hou L, Gudnason V, Ferrucci L, Launer LJ.   +14 more
europepmc   +1 more source

37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo. [PDF]

Cell Mol Life Sci
Otgaar TC, Bernert M, Morris G, Baichan P, Bignoux MJ, Letsolo B, Weiss SFT, Ferreira E.   +7 more
europepmc   +1 more source

Muscle fibre denervation in ageing. [PDF]

Clin Sci (Lond)
Soendenbroe C.
europepmc   +1 more source

Gut Microbiota-Linked Benefits of Low-Intensity Pulsed Ultrasound Rejuvenate the Ageing Muscle. [PDF]

J Cachexia Sarcopenia Muscle
Jhuang JH, Lan KC, Chang TY, Chan DC, Liu SH.   +4 more
europepmc   +1 more source

Hallmarks of the ageing lung: 10 years later. [PDF]

Eur Respir J
Baker JR, Beaulieu D, Avci E, Huang E, Eickelberg O, Meiners S, Savai R, Lehmann M, Königshoff M.   +8 more
europepmc   +1 more source