Results 21 to 30 of about 50,207 (142)
BACH2: A marker of DNA damage and ageing [PDF]
DNA Repair, 2013 DNA damage and ageing share expression changes involving alterations in many aspects of metabolism, suppression of growth and upregulation of defence and genome maintenance systems. "Omics" technologies have permitted large-scale parallel measurements covering global cellular constituents and aided the identification of specific response pathways that ...
Uittenboogaard L. M. +7 more
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Inflammatory markers in population studies of aging [PDF]
Ageing Research Reviews, 2011 To review findings from major epidemiologic studies regarding risk factors for and consequences of elevated markers of inflammation in older adults.Most large, current epidemiologic studies of older adults have measured serum interleukin-6 (IL-6), C-reactive protein (CRP) and tumor necrosis factor alpha (TNF-alpha) and some studies also include more ...
Tushar, Singh, Anne B, Newman
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Innovation in AgingAbstract Objective indicators of cognitive decline, immune function and inflammation are used as objective markers of aging (OMAs) to predict an individuals aging success. Individuals beliefs and evaluations of their own age and aging, like subjective age have been found to significantly impact longevity and health in old age, making ...
Selovin, Fabio +3 more
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Dental age is an independent marker of biological age
Human Biology and Public Health, 2022 Background: Biological age markers are a crucial indicator whether children are decelerated in growth tempo. Skeletal maturation is the standard measure. Yet, it relies on exposing children to x-radiation. Dental eruption is a potential, but highly debated, radiation free alternative.
Sonja Boeker +2 more
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Cytokeratin Markers Come of Age
Tumor Biology, 2007 Cytokeratins have been extensively used as serum tumour markers for monitoring of disease progression in cancer patients. The source of cytokeratins in the circulation as well as the mechanisms of release from cells have long been unclear. Recent evidence suggests that cytokeratins present in the circulation of cancer patients are released from ...
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Features of the apoptosis markers expression by skin cell with ageing
Бюллетень сибирской медицины, 2008 The immunohistochemical study of skin was conducted to verify presence of p53, bcl-2 and bax apoptosis markers in epidermal keratinocytes of patients from two age groups: 16 to 44 years old and 45 to 64 years old.
T. Yu. Vitruk +3 more
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Кардиоваскулярная терапия и профилактика, 2014 The review concerns on the common pathogenetic mechanisms of the atherosclerosis and osteoporosis development, and vessel wall elasticity with the decrease of bone mass and changes in bone metabolism.
I. A. Skripnikova +2 more
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Markers of biological age in dogs
Ageing Research ReviewsAs human life expectancy continues to rise, ageing and age-related diseases have become critical societal challenges, driving extensive research across genetics, molecular biology, biochemistry, and behavioral sciences. In this context, domestic dogs (Canis lupus familiaris) offer a unique model for ageing research due to their shared environmental ...
Zemko P. +9 more
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Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer
EpigeneticsBreast cancer is the most common cancer diagnosed in women and is often treated with chemotherapy. Although previous studies have demonstrated increasing biological age in patients who receive chemotherapy, evaluation of this association with DNA ...
Drew R. Nannini +3 more
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TELOMERES AND ARTERIAL HYPERTENSION: PATHOPHYSIOLOGY AND CLINICAL PERSPECTIVES
Российский кардиологический журнал, 2014 The ageing is the main risk factor for arterial hypertension (AH) and cardiovascular diseases. Natural ageing with normal BP is followed by changes in large arteries (rigidity), myocardium (hypertrophy) and diastolic relaxation and filling of cardiac ...
J. D. Kobalava, Yu. V. Kotovskaya
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