Results 71 to 80 of about 62,455 (285)

Derrida, Foucault and “Madness, the Absence of an Œuvre” [PDF]

open access: yesMeta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2011
This article argues that Foucault's 1964 paper “La folie, l'absence d'œuvre” ought to be understood as a response to Derrida's 1963 paper “Cogito et histoire de la folie”.
Seferin James
doaj  

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Loucura e razão: produzindo classes interativas

open access: yesArquivos Brasileiros de Psicologia, 2008
The article proposes a discussion of some present configurations of madness, reviewing, in the first moment, the ideas of Ian Hacking, in order to think this existence mode as an operative effect of a matrix that constitutes social interactive ...
Andrea Cristina Scisleski   +1 more
doaj  

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

open access: yesAdvanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu   +7 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

Visions of madness in William Shakespeare’s “King Lear”

open access: yesTravessias, 2018
Madness is presented as one of the main themes on the book “King Lear”, written by William Shakespeare, reaching several stages and distinct manifestations, beginning with the king’s unusual desire to share his kingdom among his three heirs while he was ...
Anderson Amaral-Oliveira   +1 more
doaj  

Madness and subjective destitution: Towards a possible exit from capitalism [PDF]

open access: yesFilozofija i Društvo
Madness, as Hegel tells us, is inherent within all, a state each of us moves through each time we acquire a new habit. Like madness, subjective destitution is also an inherent state, one each of us moves through in our initial state of being ...
Cruz Cynthia
doaj   +1 more source

In Defense of Madness: The Problem of Disability

open access: yesJournal of Medicine and Philosophy, 2018
At a time when different groups in society are achieving notable gains in respect and rights, activists in mental health and proponents of mad positive approaches, such as Mad Pride, are coming up against considerable challenges.
M. Rashed
semanticscholar   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

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