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In the 1990s, in the case of Spain, a new concept of tourism emerges that is very different from the classic one of the coast —known as sun and beach tourism—.
Alfredo Millán López +1 more
doaj +1 more source
Local politics in Spain has triggered iconic shifts over the last few years, and the electoral success of new ‘movement parties’ in particular has dramatically challenged the political establishment. Between 2015 and 2019, many municipalities – including,
Michael Janoschka, Fabiola Mota
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Cuando llegó al trono de España, Felipe V deseó una residencia de estilo francés. La elección se hizo en el Buen Retiro de Madrid, la residencia de placer de los reyes de España, cuyos edificios parecían anticuados e incómodos.
Philippe CACHAU
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Street walking quality of the ‘Centro’ district, Madrid
Walking provides a number of health, social and environmental benefits for urban sustainability, which is why it has become attractive from the perspective of sustainable transport planning.
Emilio Ortega +3 more
doaj +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
Integral management of COVID-19 in Madrid: Turning things around during the second wave.
a Clinical Microbiology and Infectious Diseases. IdISSC and IML Health Institutes. Hospital Universitario San Carlos, Madrid, Spain b Department of Medical Specialties and Public Health, Rey Juan Carlos University, Madrid, Spain c Infectious Diseases ...
Francisco José Candel +7 more
semanticscholar +1 more source
Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro +10 more
wiley +1 more source
Recursos económicos y calidad de vida en la población mayor
Una de las dimensiones que definen la Calidad de Vida de los mayores son los recursos económicos. A partir de la encuesta CadeViMa se han utilizado diversos indicadores para definir grupos de individuos significados por su valoración objetiva y subjetiva
Vicente Rodríguez-Rodríguez +6 more
doaj +1 more source

