Rapid identification of black grain eumycetoma causative agents using rolling circle amplification. [PDF]
Accurate identification of mycetoma causative agent is a priority for treatment. However, current identification tools are far from being satisfactory for both reliable diagnosis and epidemiological investigations.
Sarah A Ahmed +4 more
doaj +11 more sources
An update on the development of novel antifungal agents for eumycetoma. [PDF]
Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma.
Chandler DJ +2 more
europepmc +4 more sources
A Falciformispora senegalensis grain model in Galleria mellonella larvae. [PDF]
Eumycetoma is a subcutaneous implantation mycosis often found in the foot. One of the hallmarks of eumycetoma is the formation of grains. These grains are either black or white, and the consistency and morphology differs per causative agent. The two most
Ma J +3 more
europepmc +3 more sources
Assessing global fungal threats to humans
Abstract Fungi are an integral part of the earth's biosphere. They are broadly distributed in all continents and ecosystems and play a diversity of roles. Here, I review our current understanding of fungal threats to humans and describe the major factors that contribute to various threats.
Jianping Xu
wiley +1 more source
The development of a multiplex recombinase polymerase amplification reaction to detect the most common causative agents of eumycetoma. [PDF]
PURPOSE: Mycetoma is a neglected tropical disease that affects the subcutaneous tissue. The disease can be caused by over 90 different pathogens, including both bacteria (actinomycetoma) and fungi (eumycetoma).
Konings M +8 more
europepmc +4 more sources
Cystic form of Actinomycotic mycetoma: A new case with a diagnostic challenge
Mycetoma, commonly known as Madura foot, is a chronic granulomatous infection caused either by fungi (eumycetoma) known as actinomycete. This disease occurs preferentially in young adults, and it affects the foot in particular. We report a Tunisian case of mycetoma occurring in an old patient, particular by its cystic presentation.
Ahlem Bellalah +7 more
wiley +1 more source
Utilization of petroleum hydrocarbons by indigenous fungi isolated from a petroleum refinery effluent site in Nigeria [PDF]
No ...
Atta, H.I. +3 more
core +2 more sources
Global Burden of Human Mycetoma: A Systematic Review and Meta-analysis [PDF]
Mycetoma is a chronic infectious disease of the subcutaneous tissue with a high morbidity. This disease has been reported from countries between 30°N and 15°S since 1840 but the exact burden of disease is not known.
Sande, W.W.J. (Wendy) van de
core +10 more sources
Serious fungal infections in the Philippines [PDF]
The Philippines is a low middle-income, tropical country in Southeast Asia. Infectious diseases remain the main causes of morbidity, including tuberculosis. AIDS/HIV prevalence is still low at <1%, but is rapidly increasing.
D. Denning, M. C. R. Batac
core +1 more source
Novel Compound MMV1804559 from the Global Health Priority Box Exhibits In Vitro and In Vivo Activity against Madurella mycetomatis. [PDF]
Objectives: Eumycetoma is a neglected tropical disease (NTD) characterized by subcutaneous lesions and the formation of grains. Attempts to treat eumycetoma involve a combination of antifungal treatment and surgery, although the outcome is frequently ...
Ma J +6 more
europepmc +5 more sources

