Madurella tropicana and Madurella pseudomycetomatis identified as new causative agents of black grain eumycetoma in Senegal [PDF]
Medical Mycology Case ReportsThis study reports Madurella tropicana and Madurella pseudomycetomatis as pathogens causing eumycetoma in Senegal. The dominant species, Madurella mycetomatis, shares morphological features with both.
Maguette Faye +5 more
doaj +5 more sources
Specific and sensitive loop-mediated isothermal amplification (LAMP) method for Madurella strains, eumycetoma filamentous fungi causative agent [PDF]
PLoS Neglected Tropical Diseases, 2023 BackgroundFilamentous fungi of the genus Madurella are the primary causative agents of mycetoma, a disease observed in tropical and subtropical regions. Since early diagnostics based on a morphological approach are difficult and have many shortcomings, a
Isato Yoshioka +2 more
exaly +4 more sources
Madurella mycetomatis Is Highly Susceptible to Ravuconazole [PDF]
PLoS Neglected Tropical Diseases, 2014 The current treatment of eumycetoma utilizing ketoconazole is unsatisfactory because of high recurrence rates, which often leads to complications and unnecessary amputations, and its comparatively high cost in endemic areas.
Sarah A Ahmed +2 more
exaly +8 more sources
Canine eumycetoma caused by Madurella pseudomycetomatis
Medical Mycology Case Reports, 2022 Canine eumycetoma is a rare granulomatous disease caused by dematiaceous fungi.A 2-year-old Great Dane dog had a subcutaneous mass in the right thigh that was surgically removed. Grossly, numerous black-grains were visible.
Francesco Albanese +5 more
doaj +3 more sources
Identification of Microbial-Based Natural Products as Potential CYP51 Inhibitors for Eumycetoma Treatment: Insights from Molecular Docking, MM-GBSA Calculations, ADMET Analysis, and Molecular Dynamics Simulations [PDF]
PharmaceuticalsBackground/Objectives: Eumycetoma, caused by Madurella mycetomatis, is a chronic fungal infection with limited treatment options and increasing drug resistance.
Tilal Elsaman +4 more
doaj +2 more sources
Mycetoma due to Madurella mycetomatis
IDCases, 2020 Mycetoma is a progressive destructive disease causing severe disability, if untreated, in otherwise healthy people. Susceptible populations are usually adult males and disease is characterized by the triad of tumor formation, presence of grains and ...
L.S.M. Sigera +7 more
doaj +3 more sources
Phylogenetic Analysis of the Complete Mitochondrial Genome of Madurella mycetomatis Confirms Its Taxonomic Position within the Order Sordariales [PDF]
PLoS ONE, 2012 BACKGROUND: Madurella mycetomatis is the most common cause of human eumycetoma. The genus Madurella has been characterized by overall sterility on mycological media.
Wendy W J Van De Sande
exaly +2 more sources
PLoS Neglected Tropical Diseases, 2020 BackgroundEumycetoma is a neglected tropical disease most commonly caused by the fungus Madurella mycetomatis. Identification of eumycetoma causative agents can only be reliably performed by molecular identification, most commonly by species-specific PCR.
Wilson Lim +2 more
exaly +2 more sources
Itraconazole resistance in Madurella fahalii linked to a distinct homolog of the gene encoding cytochrome P450 14-α sterol demethylase (CYP51). [PDF]
PLoS Neglected Tropical DiseasesBackgroundMycetoma is a deep fungal infection caused by several microorganisms, with Madurella mycetomatis being the most common causative agent. Another related species, Madurella fahalii, is also known to cause eumycetoma.
Isato Yoshioka +4 more
doaj +2 more sources
Madurella real-time PCR, a novel approach for eumycetoma diagnosis
PLoS Neglected Tropical Diseases, 2020 The genus Madurella comprising four species, M. fahalii, M. mycetomatis, M. pseudomycetomatis, and M. tropicana, represents the prevalent cause of eumycetoma worldwide. The four species are phenotypically similar and cause an invariable clinical picture,
Amir Arastehfar +2 more
exaly +2 more sources