Results 31 to 40 of about 1,486 (188)

The performance and costs of XTT, resazurin, MTS and luciferin as viability dyes in in vitro susceptibility testing of Madurella mycetomatis. [PDF]

Trans R Soc Trop Med Hyg
Background in vitro susceptibility testing for the non-sporulating fungus Madurella mycetomatis is performed with a hyphal suspension as starting inoculum and a viability dye for endpoint reading.
Ma J, Eadie K, Fahal A, Verbon A, van de Sande WWJ.   +4 more
europepmc   +2 more sources

Recurrent abdominal wall mass in a hepatitis B‐positive male: An unusual case of lumbar mycetoma

Clinical Case Reports, Volume 11, Issue 12, December 2023., 2023
Key Clinical Message Atypical presentations of eumycetoma can pose a challenge in the diagnosis and treatment of the disease. Healthcare providers thorough in their differential diagnosis and investigations, even in the absence of classic symptoms, in order to improve early detection and the case management for such a neglected tropical disease ...
Alaa Tajeldeen Habeeb Abdallah, Rami Elsiddig Abdelkhalig, Elwasila Hamid, Ayman Ahmed, Emmanuel Edwar Siddig   +4 more
wiley   +1 more source

Eumicetoma por Madurella grisea: relato de caso

Revista da Sociedade Brasileira de Medicina Tropical, 1991
E relatado um caso de micetoma por Madurella grisea de localização podai em uma mulher do lar. A identificação da amostra foi feita através das características macro e microscópicas do agente em ágar Sabouraud e através da assimilação de açúcares. Este é
Maria do Rosário Rodrigues Silva, Orionalda de Fátima Lisboa Fernandes, Lilian Maria de Oliveira, Maurício Barcelos Costa, Lia Cândida de Castro   +4 more
doaj   +3 more sources

Structure-activity relationships of fenarimol analogues with potent <i>in vitro</i> and <i>in vivo</i> activity against <i>Madurella mycetomatis</i>, the main causative agent of mycetoma. [PDF]

RSC Med Chem
The fenarimol analogue EPL-BS1246 was previously discovered to be potent against Madurella mycetomatis, the causative agent of the neglected tropical disease mycetoma.
Duong HP, Melechov D, Lim W, Ma J, Scroggie KR, Rajendra L, Perry B, Cruz LR, Saleem RSZ, Rutledge PJ, Motion A, van de Sande WWJ, Todd MH.   +12 more
europepmc   +2 more sources

The impact of AlphaFold Protein Structure Database on the fields of life sciences

PROTEOMICS, Volume 23, Issue 17, September 2023., 2023
Abstract Arguably, 2020 was the year of high‐accuracy protein structure predictions, with AlphaFold 2.0 achieving previously unseen accuracy in the Critical Assessment of Protein Structure Prediction (CASP). In 2021, DeepMind and EMBL‐EBI developed the AlphaFold Protein Structure Database to make an unprecedented number of reliable protein structure ...
Mihaly Varadi, Sameer Velankar
wiley   +1 more source

Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.

PLoS Neglected Tropical Diseases, 2022
Eumycetoma is a chronic subcutaneous neglected tropical disease that can be caused by more than 40 different fungal causative agents. The most common causative agents produce black grains and belong to the fungal orders Sordariales and Pleosporales.
Wilson Lim, Bertrand Nyuykonge, Kimberly Eadie, Mickey Konings, Juli Smeets, Ahmed Fahal, Alexandro Bonifaz, Matthew Todd, Benjamin Perry, Kirandeep Samby, Jeremy Burrows, Annelies Verbon, Wendy van de Sande   +12 more
doaj   +1 more source

Evaluation of the Antiparasitic and Antifungal Activities of Synthetic Piperlongumine‐Type Cinnamide Derivatives: Booster Effect by Halogen Substituents

ChemMedChem, Volume 18, Issue 12, June 15, 2023., 2023
Halo‐ed ground: New piperlongumine‐type cinnamides with halogen substituents and the potential to bind tubulin show considerable activities against Toxoplasma gondii and Leishmania major protozoal parasites, and moderate activity against Trypanosoma brucei and Madurella mycetomatis, depending on the halogen atom present.
Tariq A. Khan, Ibrahim S. Al Nasr, Waleed S. Koko, Jingyi Ma, Simon Eckert, Lucas Brehm, Ridha Ben Said, Ismail Daoud, Riadh Hanachi, Seyfeddine Rahali, Wendy W. J. van de Sande, Klaus Ersfeld, Rainer Schobert, Bernhard Biersack   +13 more
wiley   +1 more source

Madurella pseudomycetomatis: an Invalidly Published Name [PDF]

Journal of Clinical Microbiology, 2011
The taxon Madurella pseudomycetomatis was recently proposed as a new species in a paper by Yan et al. ([2][1]). It was isolated from black granules of the discharging sinuses on the lower jaw of a 27-year-old patient from China.
Arvind A, Padhye, Ira F, Salkin
openaire   +2 more sources

Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176. [PDF]

Mycopathologia
Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M.
Konings M, Gerrits van den Ende B, Raats MWJ, Fahal AH, van de Sande WWJ, Hagen F.   +5 more
europepmc   +2 more sources

Comparing the performance of the common used eumycetoma diagnostic tests

Mycoses, Volume 66, Issue 5, Page 420-429, May 2023., 2023
Abstract Objectives Mycetoma is a neglected tropical implantation disease caused by 70 different infectious agents. Identifying the causative organism to the species level is essential for appropriate patient management. Ultrasound, histopathology, culture and two species‐specific PCRs are most the commonly used methods for species identification in ...
Emmanuel Edwar Siddig, Bertrand Nyuykonge, Najwa Adam Mhmoud, Omnia Babekir Abdallah, Mustafa El Nour Bahar, Eiman Siddig Ahmed, Borna Nyaoke, Eduard E. Zijlstra, Annelies Verbon, Sahar Mubarak Bakhiet, Ahmed Hassan Fahal, Wendy W. J. van de Sande   +11 more
wiley   +1 more source