Results 41 to 50 of about 1,486 (188)

The combination of manogepix and itraconazole is synergistic and inhibits the growth of Madurella mycetomatis in vitro but not in vivo

Medical Mycology, 2023
Mycetoma is a neglected tropical disease commonly caused by the fungus Madurella mycetomatis. Standard treatment consists of extensive treatment with itraconazole in combination with surgical excision of the infected tissue, but has a low success rate ...
Mickey Konings, K. Eadie, Nikolaos Strepis, B. Nyuykonge, A. Fahal, Annelies Verbon, W. V. D. van de Sande   +6 more
semanticscholar   +1 more source

Eumicetoma de grãos pretos por Madurella grisea: registro de dois casos Eumycotic mycetoma of black grains caused by Madurella grisea: report of two cases

Revista do Instituto de Medicina Tropical de São Paulo, 1992
Os Autores registram dois casos de eumicetoma de grãos pretos, com localização podal, procedentes da Bahia, provocados por Madurella grisea Mackinnon et al., 1949.
Luís Antonio de Paula Machado, Maria Cecília da Matta Rivitti, Luís Carlos Cucé, Alberto Salebian, Carlos da Silva Lacaz, Elisabeth Maria Heins-Vaccari, Walter Belda Jr., Natalina Takahashi de Melo   +7 more
doaj   +1 more source

A Novel Report of mycetoma with Spinal Spread due to Madurella fahalli from India.

Indian Journal of Medical Microbiology, 2023
Eumycetoma caused by Madurella fahalii, a drug-resistant fungus, has never been reported in India. Here, we describe a fatal case of eumycetoma with spinal involvement due to M. fahalii for the first time in India.
V. Hallur, Chandra Sekar Sirka, Mukund Sable, Madhusmita Sethy, N. Bag, Supriya Sahu, Malaya Sahoo, M. Shivaprakash, Madhuchhanda Das   +8 more
semanticscholar   +1 more source

Diagnostics to support mycetoma management—Development of two target product profiles

Tropical Medicine &International Health, Volume 27, Issue 12, Page 1059-1064, December 2022., 2022
Abstract Objective Mycetoma is a neglected tropical disease caused by more than 70 different microorganisms and identified by the WHO as one of the high‐priority diseases for developing diagnostic tests. To ensure the production of diagnostic assays for use by clinical staff in endemic regions, target product profiles (TPPs) were designed.
Noah Fongwen, Kingsley B. Asiedu, Sahar Bakhiet, Alexandro Bonifaz, Israel Cruz, Daniel Argaw, Guadalupe Estrada‐Chavez, Ahmed H. Fahal, Ana Litvintseva, Michael Marks, Mario C. Salinas‐Carmona, Doudou Sow, Wendy W. J. van de Sande   +12 more
wiley   +1 more source

Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella

Medical Mycology, 2022
Eumycetoma is a neglected tropical disease, and Madurella mycetomatis, the most common causative agent of this disease forms black grains in hosts. Melanin was discovered to be one of the constituents in grains.
W. Lim, Mickey Konings, Florianne Parel, K. Eadie, Nikolaos Strepis, A. Fahal, A. Verbon, W. V. D. van de Sande   +7 more
semanticscholar   +1 more source

Madurella mycetomatis causing eumycetoma medical treatment: The challenges and prospects.

PLoS Neglected Tropical Diseases, 2020
Mycetoma is a WHO recognised neglected tropical disease that is a subcutaneous chronic granulomatous progressively morbid inflammatory disease [1]. It frequently affects young adults and children in remote rural areas.
Lamis Y M Elkheir, Rayan Haroun, Magdi Awadalla Mohamed, Ahmed Hassan Fahal   +3 more
doaj   +2 more sources

A murine model ofMadurella mycetomatiseumycetoma [PDF]

FEMS Immunology & Medical Microbiology, 2003
Eumycetoma due to Madurella mycetomatis is a major mycological health problem in endemic areas. We infected BALB/c mice (male or female) with various amounts of M. mycetomatis mycelium, containing sterilized soil as a natural adjuvant or Freund's incomplete adjuvant. Mice differed with respect to age and immune status. Intraperitoneal, subcutaneous and
Ahmed, AOA (Abdalla), van Vianen, W (Wim), ten Kate, Marian, Laureijssen - van de Sande, Wendy, Belkum, Alex, Fahal, AH, Verbrugh, Henri, Woudenberg, Irma   +7 more
openaire   +2 more sources

Erratum for Abd Algaffar et al., "Development and Validation of an In Vitro Resazurin-Based Susceptibility Assay against Madurella mycetomatis". [PDF]

Antimicrob Agents Chemother
Abd Algaffar SO, Verbon A, van de Sande WWJ, Khalid SA.   +3 more
europepmc   +2 more sources

Recurrent eumycetoma caused by novel species Madurella pseudomycetomatis: A case report

Medical Mycology Case Reports, 2019
Mycetoma is a chronic-granulomatous disease characterized by the inflammation, swollen organ, draining sinuses containing blood, pus, and grains. We present a case of madura foot with novel etiologic agent Madurella pseudomycetomatis. Diagnosis was based
Zeinab Borjian Boroujeni, Seyed Jamal Hashemi, Roshank Daie Ghazvini, Sadegh Khodavaisy, Mahdi Zareei, Leila Hosseinpour, Pegah Ardi, Mohammad Shokri   +7 more
doaj   +1 more source

Sandalwood Oils of Different Origins Are Active In Vitro against <i>Madurella mycetomatis</i>, the Major Fungal Pathogen Responsible for Eumycetoma. [PDF]

Molecules
In the search for new bioactive agents against the infectious pathogen responsible for the neglected tropical disease (NTD) mycetoma, we tested a collection of 27 essential oils (EOs) in vitro against Madurella mycetomatis, the primary pathogen ...
Abd Algaffar SO, Seegers S, Satyal P, Setzer WN, Schmidt TJ, Khalid SA.   +5 more
europepmc   +2 more sources