Results 61 to 70 of about 1,815 (196)

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Phaeohyphomycosis caused by Trematosphaeria grisea in an immunocompromised English springer spaniel

Veterinary Record Case Reports, Volume 12, Issue 4, December 2024.
Abstract A 10‐year‐old, male, farm‐based springer spaniel that presented with subacute progressive left‐sided central vestibular signs was diagnosed with meningoencephalitis of unknown origin. The patient received prednisolone (2 mg/kg/day orally), ciclosporin (5 mg/kg orally twice a day) and a single infusion of cytarabine (200 mg/m2). Six weeks later,
Erin Brennan, Theofanis Liatis, Sian‐Marie Frosini, Elizabeth Johnson, Ross Bond   +4 more
wiley   +1 more source

Reverse line blot hybridization assay for identification of medically important fungi from culture and clinical specimens [PDF]

, 2007
We evaluated a combined panfungal PCR-reverse line blot (RLB) hybridization assay based on internal transcribed spacer 1 (ITS1) and ITS2 region polymorphisms to identify 159 Candida, Cryptococcus neoformans, and Aspergillus isolates (22 species).
Zeng, Xianyu, Kong, Fanrong, Halliday, Catriona, Chen, Sharon, Lau, Anna, Playford, Geoffrey, Sorrell, Tania C.   +6 more
core   +1 more source

Photokatalytische CO2 Reduktion mit CO2‐bindenden Enzymen

Angewandte Chemie, Volume 136, Issue 16, April 15, 2024.
Es wird eine neue, vielseitige Aktivität der Phenolsäure‐Decarboxylase aus Bacillus subtilis und anderer CO2‐bindender Enzyme beschrieben. Die Enzyme katalysieren die photokatalytische CO2‐Reduktion in Gegenwart eines Ru(bpy)3‐Photosensibilisators, wobei sie eine hohe Selektivität für die CO2‐Reduktion gegenüber der Protonenreduktion (bis zu 93 ...
Henrik Terholsen, Hilario Diego Huerta‐Zerón, Christina Möller, Henrik Junge, Matthias Beller, Uwe T. Bornscheuer   +5 more
wiley   +1 more source

Indoor air pollutants in occupational buildings in a sub-tropical climate: Comparison among ventilation types [PDF]

, 2016
© 2016 Elsevier Ltd. Few studies have concurrently assessed both abiotic and biotic air pollutants in the built environment in sub-tropical areas.
Irga, PJ, Torpy, FR
core   +1 more source

Photocatalytic CO2 Reduction Using CO2‐Binding Enzymes

Angewandte Chemie International Edition, Volume 63, Issue 16, April 15, 2024.
A novel promiscuous activity of the phenolic acid decarboxylase from Bacillus subtilis and other CO2‐binding enzymes is described. The enzymes catalyze the photocatalytic CO2 reduction in the presence of a Ru(bpy)3 photosensitizer, exhibiting high selectivity for CO2 reduction over proton reduction (up to 93 %).
Henrik Terholsen, Hilario Diego Huerta‐Zerón, Christina Möller, Henrik Junge, Matthias Beller, Uwe T. Bornscheuer   +5 more
wiley   +1 more source

A Retrospective Review of Neglected Tropical Diseases Diagnosed on Histopathological Specimens in the Free State Province, South Africa, 2015–2020

Journal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Background. Neglected tropical diseases (NTDs) are a heterogeneous group of medical conditions that commonly occur in underprivileged populations. NTDs are primarily diagnosed in tropical areas. Although South Africa is not situated in a tropical region, the high poverty rate makes the country susceptible to some NTDs. Limited data are available on the
Danita Linda le Grange, She’neze Fatima Pillay, Liska Budding, Cornel van Rooyen, Jacqueline Goedhals, Faham Khamesipour   +5 more
wiley   +1 more source

The genus Madurella: Molecular identification and epidemiology in Sudan.

PLoS Neglected Tropical Diseases, 2020
Eumycetoma (mycotic mycetoma) is the fungal form of mycetoma, a subcutaneous infection occurring in individuals living in endemic areas of the disease.
Elhadi A Ahmed, Bakri Y M Nour, Adam D Abakar, Samirah Hamid, Ahmed A Mohamadani, Mohamed Daffalla, Mogahid Mahmoud, Hisham N Altayb, Marie Desnos-Ollivier, Sybren de Hoog, Sarah A Ahmed   +10 more
doaj   +1 more source

Environmental detection of eumycetoma pathogens using multiplex real-time PCR for soil DNA in Sennar State, Sudan

Tropical Medicine and Health, 2023
Background Mycetoma is a chronic disease affecting the skin and subcutaneous tissue endemic in the tropical and subtropical regions. Several bacteria and fungi can cause mycetoma, but fungal mycetoma (eumycetoma) is challenging because the treatment ...
Hiroki Hashizume, Suguru Taga, Masayuki K. Sakata, Mahmoud Hussein, Emmanuel Edwar Siddig, Toshifumi Minamoto, Ahmed Hassan Fahal, Satoshi Kaneko   +7 more
doaj   +1 more source

A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma. [PDF]

J Antimicrob Chemother
BackgroundMycetoma caused by Madurella mycetomatis (eumycetoma) is a neglected tropical disease that forms tumorous lesions in the subcutaneous tissue. The current standard treatment for eumycetoma consists of antifungal treatment combined with surgery ...
Ma J, van Doodewaerd BR, Biersack B, Verbon A, Geurink PP, van de Sande WWJ.   +5 more
europepmc   +3 more sources