Results 11 to 20 of about 1,815 (196)

A histopathological exploration of the Madurella mycetomatis grain. [PDF]

PLoS ONE, 2013
Although the Madurella mycetomatis grains seem to interfere with the host defense mechanisms and impede the antifungal drugs penetration, yet their histological features are not fully known and hence this study was set out to determine that.
Anahid Izzat Ibrahim, Ahmed Mohammed El Hassan, Ahmed Fahal, Wendy W van de Sande   +3 more
doaj   +7 more sources

Left Gluteal and Perianal Eumycetoma Lesion Extending Into the Left Greater Sciatic Foramen, Pelvic Cavity to the External Anal Sphincter [PDF]

Clinical Case Reports
Mycetoma is a chronic subcutaneous infection that primarily affects the lower extremities, although atypical anatomical presentations are possible.
Rawa Badri, Ahmed Hassan Fahal
doaj   +3 more sources

Phylogenetic findings suggest possible new habitat and routes of infection of human eumyctoma. [PDF]

PLoS Neglected Tropical Diseases, 2013
Eumycetoma is a traumatic fungal infection in tropical and subtropical areas that may lead to severe disability. Madurella mycetomatis is one of the prevalent etiologic agents in arid Northeastern Africa.
G Sybren de Hoog, Sarah A Ahmed, Mohammad J Najafzadeh, Deanna A Sutton, Maryam Saradeghi Keisari, Ahmed H Fahal, Ursala Eberhardt, Gerard J Verkleij, Lian Xin, Benjamin Stielow, Wendy W J van de Sande   +10 more
doaj   +4 more sources

Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker. [PDF]

PLoS Neglected Tropical Diseases
Madurella mycetomatis is the main cause of mycetoma, a chronic granulomatous infection for which currently no adequate therapy is available. To improve therapy, more knowledge on a molecular level is required to understand how M.
Saskia du Pré, Mickey Konings, Dorenda J A Schoorl, Ahmed H Fahal, Mark Arentshorst, Arthur F J Ram, Wendy W J van de Sande   +6 more
doaj   +4 more sources

Antifungal Activity of Natural Naphthoquinones and Anthraquinones against Madurella mycetomatis [PDF]

Chemistry &Biodiversity, Volume 20, Issue 5, May 2023., 2023
Eumycetoma, the fungal form of the neglected tropical disease mycetoma, is a crippling infectious disease with low response rates to currently available antifungal drugs. In this study, a series of natural naphthoquinones and anthraquinones was evaluated
Biersack, Bernhard, Ma, Jingyi, Todd, Matthew, van de Sande, Wendy W. J.   +3 more
core   +4 more sources

Eumycotic mycetoma due to Madurella grisea [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1989
The authors reported one case of eumycotic mycetoma due to Madurella grisea (black grains) occurred on the right foot of the patient studied. The structure, microscopic morphology and therapeutic evolution are also studied and reported.
Walter Belda Júnior, Luis Carlos Cucé, Mabel Cristina Dias, Carlos da Silva Lacaz   +3 more
doaj   +3 more sources

The contribution of mycetoma grains to suboptimal disease management [PDF]

Nature Communications
A defining feature of mycetoma is the presence of grains, which are dense, compact structures composed of the causative bacterial or fungal microorganisms.
Ahmed Hassan Fahal, Abdalla Osaman Ahmed, Lamyaa El Hassan, Ali Awadallah Saeed   +3 more
doaj   +2 more sources

Diagnosis and Management of a Long-Standing Eumycetoma of the Wrist in Somalia: A Case Report in a Resource-Limited Setting [PDF]

International Medical Case Reports Journal
Adam Abdulahi Mohamed,1,2 Shafie Abdulkadir Hassan,3 Mhmoud Mohmed Mhmoud Hassan1 1Center for Mycetoma Research, Mogadishu, Somalia; 2Faculty of Health Sciences, Central University of Science and Technology, Baladweyn, Hiiran, Somalia; 3Faculty of ...
Mohamed AA, Hassan SA, Hassan MMM
doaj   +2 more sources

Rapid identification of black grain eumycetoma causative agents using rolling circle amplification. [PDF]

PLoS Neglected Tropical Diseases, 2014
Accurate identification of mycetoma causative agent is a priority for treatment. However, current identification tools are far from being satisfactory for both reliable diagnosis and epidemiological investigations.
Sarah A Ahmed, Bert H G Gerrits van den Ende, Ahmed H Fahal, Wendy W J van de Sande, G S de Hoog   +4 more
doaj   +11 more sources

Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis. [PDF]

PLoS Neglected Tropical Diseases
Eumycetoma is a neglected tropical subcutaneous disease most commonly caused by the fungus Madurella mycetomatis. Currently, eumycetoma is treated by a combination of antifungal therapy and surgery, with limited success rates.
Mickey Konings, Nikolaos Strepis, Ri-Ichiroh Manabe, Akira Hasegawa, Somdatta Chaudhari, Saskia du Pré, Marij Schippers, Michihira Tagami, Jingyi Ma, Yasushi Okazaki, Matthew Todd, Bernhard Biersack, Vijay Masand, Annelies Verbon, Takeya Kasukawa, Imad Abugessaisa, Wendy W J van de Sande   +16 more
doaj   +2 more sources