Results 131 to 140 of about 503,578 (359)
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová+14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
El papel de la aprehensión de los actos de habla en la comprensión de los enunciados.
La teoría de los actos de habla afirma que para comprender un enunciado, es necesario reconocerlo como un acto ilocutivo. Sperber y Wilson (1986) toman una postura contraria al respecto, pero ninguna de las dos propuestas presenta suficiente evidencia ...
Hugo García Macías
doaj +2 more sources
Datos acerca de varios maestros salmantinos [PDF]
Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Separata de: Homenaje a Menéndez Pidal. T.
Alonso Cortés, Narciso, 1875-1972
core +1 more source
SensRORing cholesterol to drive protumoral myelopoiesis
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley +1 more source
Spiralling Pre-clerkship Concepts into the Clinical Phase: Augmenting Knowledge Transfer Using Innovative Technology-Enhanced Curriculum Activities. [PDF]
Bracken K+5 more
europepmc +1 more source
Space, mass and ornament in the Gothic-Renaissance transition in Spain [PDF]
La introducción en España de las nuevas formas y sintaxis renacentistas a lo largo del siglo xvi no se produjo con un abandono radical e inmediato de los viejos usos góticos, de validez comprobada en trascendentales cuestiones del diseño ...
García Ortega, Antonio Jesús+1 more
core
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin+10 more
wiley +1 more source
Absolute quantification of cerebral tissue oxygen saturation with multidistance broadband NIRS in newborn brain. [PDF]
Kovacsova Z+4 more
europepmc +1 more source