Results 131 to 140 of about 87,748 (307)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Retos a resolver en la formación a distancia de la Escuela Superior de Comercio y Administración Unidad Santo Tomás del Instituto Politécnico Nacional

open access: yesRECIE Revista Electrónica Científica de Investigación Educativa, 2016
Esta ponencia es sobre una investigación realizada por parte de la Subdirección Académica y docentes de la Escuela Superior de Comercio y Administración, Unidad Santo Tomás (ESCASTO), del Instituto Politécnico Nacional (IPN).
Elia Olea Deserti   +2 more
doaj  

Maestro Platform-Generated Dataset of Classified sound files

open access: green, 2023
Alexandre Magalhães Serra   +2 more
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Motivación e innovación: Aceptación de tecnologías móviles en los maestros en formación

open access: diamond, 2017
José Carlos Sánchez‐Prieto   +2 more
openalex   +2 more sources

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