Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
La educación ambiental integral como derecho de las infancias
Revista in-fan-cia Latinoamericana
doaj +1 more source
Polyphenols from Bacopa procumbens Nanostructured with Gold Nanoparticles Stimulate Hair Growth Through Apoptosis Modulation in C57BL/6 Mice. [PDF]
Pérez-Mora S+5 more
europepmc +1 more source
In Vivo and Ex Vivo Evaluation of 1,3-Thiazolidine-2,4-Dione Derivatives as Euglycemic Agents. [PDF]
Alemán-González-Duhart D+4 more
europepmc +1 more source
A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou+5 more
wiley +1 more source
[Psychological impact of lockdown (confinement) on young children and how to mitigate its effects: Rapid review of the evidence]. [PDF]
García Ron A, Cuéllar-Flores I.
europepmc +1 more source
Chemical Constituents, In Vitro Antioxidant Activity and In Silico Study on NADPH Oxidase of Allium sativum L. (Garlic) Essential Oil. [PDF]
Herrera-Calderon O+5 more
europepmc +1 more source