Results 181 to 190 of about 183,801 (267)

Clinically actionable pharmacogenomic variants for anticancer therapy in Nigeria: first comprehensive variant profiling in underrepresented Nigerian cohorts. [PDF]

BMC Med Genomics
Ukpe MP, Ezeanuka AC.
europepmc   +1 more source

Identification and functional validation of a novel disease‐causing variant in the noncoding region of NYX

Acta Ophthalmologica, EarlyView.
Abstract Purpose Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, with ~30% of cases remaining genetically unsolved. Complete congenital stationary night blindness (cCSNB) is a subtype of IRD, usually associated with reduced visual acuity, nystagmus and high myopia.
Filip Spanic, Christelle Michiels, Julien Navarro, Aline Antonio, Christel Condroyer, Camille Andrieu, Billy Gipsy, Sylvie Berthémy‐Pellet, Mathilde Gallice, Isabelle Audo, Christina Zeitz   +10 more
wiley   +1 more source

Distribution of <i>NUDT15*4</i> in Native American populations of the Brazilian Amazon and risk of intolerance to thiopurine drugs. [PDF]

Front Pharmacol
Suarez-Kurtz G, Elias ABR, Carvaho MA, Dias A, Gusmão L, Basta PC, Perini JA.   +6 more
europepmc   +1 more source

Associations Between Obesity, Diabetes Mellitus, and Pancreatic Cancer in the Japanese Population: A Mendelian Randomization Study

Cancer Science, EarlyView.
Our Mendelian Randomization analysis provides evidence supporting a causal association between genetic predisposition to T2D, independent of BMI, and an increased risk of pancreatic cancer in the Japanese population, corroborating findings from observational studies.
Yingsong Lin, Haruki Sasado, Naoki Sasahira, Makoto Ueno, Hiroshi Ishii, Naoto Egawa, Yasushi Adachi, Masato Ozaka, Satoshi Kobayashi, Yuriko N. Koyanagi, Sayaka Yamamoto, Hidemi Ito, Akira Narita, Mika Sakurai‐Yageta, Takuji Okusaka, Aya Kuchiba, Teruhiko Yoshida, Fumihiko Matsuda, Yoichiro Kamatani, Shiori Nakano, Taiki Yamaji, Norie Sawada, Aya Kadota, Kiyonori Kuriki, Takeshi Watanabe, Nobuo Fuse, Kengo Kinoshita, Naoki Nakaya, Yoichi Sutoh, Yayoi Otsuka‐Yamasaki, Kozo Tanno, Ken Suzuki, Toshimasa Yamauchi, Takashi Kadowaki, BioBank Japan, Motoki Iwasaki, Sho Nakamura, Atsushi Hozawa, Atsushi Shimizu, Shogo Kikuchi, Masahiro Nakatochi, Keitaro Matsuo   +41 more
wiley   +1 more source

Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations. [PDF]

Nat Commun
Hawkes G, Wright HIW, Beaumont RN, Chundru K, Hanson A, Jackson L, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Weedon MN.   +11 more
europepmc   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

<i>NR3C1</i>, <i>LAX1</i>, and <i>RCAN3</i> as Circulating Epigenetic Biomarkers for Prognosis and Chemotherapy Response Prediction in Metastatic Pancreatic Cancer. [PDF]

MedComm (2020)
Cano-Ramírez P, Toledano-Fonseca M, Cano-Osuna MT, Herrera-Casanova N, Carrillo-Pecero E, Rodríguez-Ariza A, Aranda E, García-Ortiz MV.   +7 more
europepmc   +1 more source

Children's Intimate Partner Violence Exposure and Mothers' Eviction Stress

Child &Family Social Work, EarlyView.
ABSTRACT Intimate partner violence has profound impacts on the housing insecurity of mothers and children. Abusers may control household finances, cause property damage or nuisance complaints, or create financial dependence that prevents survivors from fleeing.
Kathryn Showalter, Katherine Marcal, Lijian Zhao, Kathryn Maguire‐Jack, Yanghyun Park, Yinqi Chen   +5 more
wiley   +1 more source

Whole-Exome Sequencing for the Identification of Genetic Factors Implicated in Severe Bacterial Infections: A Systematic Review. [PDF]

J Infect Dis
Gélin M, Launay É, Vince N.
europepmc   +1 more source

The plasticisation model of dye diffusion: Part 7

Coloration Technology, EarlyView.
Abstract Re‐evaluation using the Williams‐Landel‐Ferry equation, of exhaustion/fixation/adsorption data previously reported for four classes of anionic dye onto three different types of wool substrate, revealed that thermally activated dyeing/desorption behaviour is governed by the thermally regulated structural relaxation times of the respective water‐
Stephen M. Burkinshaw
wiley   +1 more source