Results 91 to 100 of about 112,453 (312)

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Magic moments [PDF]

Nuclear Physics B, 1981
J. S. BELL, R. A. BERTLMANN
openaire   +1 more source

MAGIC detection of sub-TEV emission from gravitationally lensed blazar QSO B0218+357 [PDF]

, 2016
D. Dominis Prester, J. Sitarek, J. Becerra, S. Buson, E. Lindfors, M. Manganaro, D. Mazin, M. Nievas Rosillo, K. Nilsson, A. Stamerra, F. Tavecchio, I. Vovk, for the MAGIC Coll., the Fermi-LAT Coll.   +13 more
openalex   +1 more source

Magic and Antimagic Decomposition of Amalgamation of Cycles [PDF]

, 2022
Sigit Pancahayani, Annisa Rahmita Soemarsono, Dieky Adzkiya, Musyarofah Musyarofah   +3 more
openalex   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Radiation response and basic dosimetric characterisation of the ‘Magic Plate’ [PDF]

, 2017
Z.A. Alrowaili, Michael Lerch, Marco Petasecca, Martin Carolan, Anatoly Rosenfeld   +4 more
openalex   +1 more source

Magic angles in twisted bilayer graphene near commensuration: Towards a hypermagic regime [PDF]

, 2022
Michael G. Scheer, Kaiyuan Gu, Biao Lian
openalex   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Interpretation and Conducting of Jin Chengzhi's Magic City Chinese Choral Works [PDF]

, 2023
Liu Wenwei, Yap Jin Hin
openalex   +1 more source

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source