Results 91 to 100 of about 303,849 (285)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Tribotechnical properties of coatings based on magnesium compounds

open access: yesПроблеми трибології
The article summarizes the results of studies of tribotechnical properties of detonation coatings based on magnesium orthosilicate under conditions of constant load in the sliding velocity field.
V.V. Shchepetov, N.M. Fialko, S.S. Bys
doaj   +1 more source

Electrochemical Behavior of Magnesium and its Alloys in non-Aqueous Solutions

open access: yesEurasian Chemico-Technological Journal, 2001
Magnesium and its alloys are widely used in creation of chemical sources of current, because possesses a number of characteristics: highly negative standart potential, low equivalent weight, high melting point, low cost, relative abundance, ease of ...
A. M. Kuvancheva   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

The oxidation state in low-valent beryllium and magnesium compounds. [PDF]

open access: yesChem Sci, 2022
Gimferrer M   +7 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Stress relief treatment of aluminum/magnesium laminates fabricated by roll bonding technique

open access: yesHeliyon
Roll bonding of aluminum/magnesium laminates combines the good corrosion resistance of aluminum alloys with the beneficial mechanical properties of magnesium alloys. We studied the microstructure of aluminum Al-1051/AZ31 magnesium laminates fabricated by
Masoud Rashidi   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Research progress in effects of Sm on structural and functional properties of magnesium alloys

open access: yesCailiao gongcheng
Magnesium alloy is a lightweight metallic material with huge potential for application in automobile, rail transit and aerospace, it can provide a solid support for the green and low-carbon development of China’s manufacturing industry.
LIU Feng   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy