Results 41 to 50 of about 51,953 (279)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

New Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini, I. Magouras, C. Chapuis‐Taillard, O. Clerc, E. Masserey, G. Peduto, O. Péter, S. Schaerrer, G. Schuepbach, G. Greub   +9 more
wiley   +1 more source

Evaluation of micronutrients among pediatric liver cirrhosis in Shiraz, Iran

Egyptian Liver Journal, 2022
Background Cirrhosis is the final result of most types of liver disease. Zinc, magnesium, and vitamin D have a significantly vital role in the immunologic and physiologic mechanisms in the body.
Seyed Mohsen Dehghani, Anis Amirhakimi, Parisa Baligh, Hazhir Javaherizadeh   +3 more
doaj   +1 more source

Ground-state properties and symmetry energy of neutron-rich and neutron-deficient Mg isotopes [PDF]

, 2014
A comprehensive study of various ground-state properties of neutron-rich and neutron-deficient Mg isotopes with $A$=20-36 is performed in the framework of the self-consistent deformed Skyrme-Hartree-Fock plus BCS method. The correlation between the skin thickness and the characteristics related with the density dependence of the nuclear symmetry energy
arxiv   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The relationship between magnesium deficiency and depression, and the effects of magnesium supplementation on depression symptoms – literature review

Journal of Education, Health and Sport, 2022
Magnesium is a very important macronutrient in the human body. Its main storage is bones. The correct concentration of this macronutrient within the normal range is necessary for the proper functioning of the body.
Dominik Machaj, Alicja Płaczek, Dominik Machaj, Patrycja Baciur, Katarzyna Skowrońska   +4 more
doaj   +1 more source

Pressure shifts and abundance gradients in the atmosphere of the DAZ white dwarf GALEX J193156.8+011745 [PDF]

, 2011
We present a detailed model atmosphere analysis of high-dispersion and high signal-to-noise ratio spectra of the heavily polluted DAZ white dwarf GALEX J1931+0117. The spectra obtained with the VLT-Kueyen/UV-Visual Echelle Spectrograph show several well-resolved Si II spectral lines enabling a study of pressure effects on line profiles.
arxiv   +1 more source

Precision mass measurements of magnesium isotopes and implications on the validity of the Isobaric Mass Multiplet Equation [PDF]

Phys. Rev. C 96, 034316 (2017), 2017
If the mass excess of neutron-deficient nuclei and their neutron-rich mirror partners are both known, it can be shown that deviations of the Isobaric Mass Multiplet Equation (IMME) in the form of a cubic term can be probed. Such a cubic term was probed by using the atomic mass of neutron-rich magnesium isotopes measured using the TITAN Penning trap and
arxiv   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

High resolution spectroscopy of the relatively hydrogen-poor metal rich giants in the globular cluster Omega Centauri [PDF]

, 2018
High-resolution optical spectra are analyzed for two of the four metal rich mildly hydrogen-poor or helium-enhanced giants discovered by Hema and Pandey (2014) along with their comparison normal (hydrogen-rich) giants of Omega Cen. The strengths of the MgH bands in the spectra of the program stars are analyzed for their derived stellar parameters.
arxiv   +1 more source