Results 41 to 50 of about 9,287 (256)

Research progress on nanoparticles reinforced magnesium alloys

Journal of Materials Research and Technology
Magnesium alloys, acknowledged as the environmentally-friendly engineering material of the 21st century, are ideally suited to fulfill the requirements of lightweight manufacturing.
Yu-Xin Luo, Bai-Xin Dong, Hong-Yu Yang, Feng Qiu, Bai-Chuan Yan, Shi-Li Shu, Qi-Chuan Jiang, Feng-Jian Shi   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Modeling of transverse welds formation during liquid–solid extrusion directly following vacuum infiltration of magnesium matrix composite

Journal of Magnesium and Alloys, 2015
Liquid–solid extrusion directly following vacuum infiltration (LSEVI) is an infiltration–extrusion integrated forming technique, and transverse weld between upper residual magnesium alloy and magnesium matrix composites is a common internal defect, which
Jian Liu, Lehua Qi, Haiyan Zhang, Heping Hou   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fabrication and mechanical properties of high-strength AZ61Mg‒18%Ti composites

Fenmo yejin jishu, 2021
The AZ61Mg‒18%Ti (mass fraction) composites were prepared by mechanical milling, vacuum hot pressing, and hot extrusion. The microstructure, room-temperature mechanical properties, and the corresponding strengthening mechanism were studied.
ZHANG Xiao-hong, YU Huan, HU Lian-xi
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Hybrid heterophasic polypropylene composites with basalt fibers and Magnesium oxysulfate reinforcements for sustainable automotive materials

Journal of Materials Research and Technology
Hybrid heterophasic polypropylene (PP) composites comprising basalt fibers and Magnesium oxysulfate reinforcements were fabricated for the next generation of automobile plastic parts. The prepared composites were tested and characterized for their thermo-
K.V. Balaji, Kamyar Shirvanimoghaddam, Ramdayal Yadav, Roya Mahmoodi, Mahmoud Reza Ghandehari Ferdowsi, Minoo Naebe   +5 more
doaj   +1 more source

Microstructure and Mechanical Behavior of Al-Mg Composites Synthesized by Reactive Sintering

Metals, 2018
Lightweight metal matrix composites are synthesized from elemental powder mixtures of aluminum and magnesium using pressure-assisted reactive sintering.
Rub Nawaz Shahid, Sergio Scudino
doaj   +1 more source

Construction of homogeneous structure and chemical bonding in bamboo scrap/magnesium oxychloride composites by polycarboxylate superplasticizer

Journal of Materials Research and Technology, 2021
This study was aimed to solve the problem of large waste from bamboo processing residues, improve the quality of building composites, give composites biological properties, and expand the use of composites.
Long Zheng, Yingfeng Zuo, Ping Li, Shu Wang, Guoan Sheng, Yiqiang Wu   +5 more
doaj   +1 more source