Results 91 to 100 of about 903,606 (393)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Jappe, Anselm; Maiso, Jordi; Rojo, José Manuel: Criticar el valor, superar el capitalismo.

Oxímora. Revista Internacional de Ética y Política, 2015
La agudización de la crisis del capitalismo a la que estamos asistiendo -por lo menos de forma nítida desde el año 2008- ha favorecido la difusión internacional de los planteamientos de los teóricos del valor.
Jordi Magnet Colomer
doaj   +1 more source

Rotating sample magnetometer for cryogenic temperatures and high magnetic fields

, 2011
We report on the design and implementation of a rotating sample magnetometer (RSM) operating in the variable temperature insert of a cryostat equipped with a high-field magnet.
Eisterer, M., Hecher, J., Hengstberger, F., Hörhager, N., Sorta, S., Voutsinas, C. S., Weber, H. W.   +6 more
core   +1 more source

Simulation of the Braking Effects of Permanent Magnet Eddy Current Brake and Its Effects on Levitation Characteristics of HTS Maglev Vehicles [PDF]

, 2022
Gaowei Zhang, Jianmei Zhu, Yan Li, Yuhang Yuan, Yuqing Xiang, Peng Lin, Li Wang, Jianxin Liu, Le Liang, Zigang Deng   +9 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

¿Una crítica inmanente radical? Entrevista a José Manuel Romero Cuevas

Oxímora. Revista Internacional de Ética y Política, 2016
José Manuel Romero Cuevas (Sanlúcar de Barrameda, 1970) es profesor en la Universidad de Alcalá (Madrid). Se doctoró en la Universidad de Granada (UGR) con una tesis sobre el problema del conocimiento en F.
Jordi Magnet Colomer
doaj   +1 more source

Electron spin resonance study of anisotropic interactions in a two-dimensional spin gap magnet PHCC

, 2011
Fine details of the excitation spectrum of the two-dimensional spin-gap magnet PHCC are revealed by electron spin resonance investigations. The values of anisotropy parameters and the orientations of the anisotropy axes are determined by accurate ...
A. Abragam, A. Zheludev, D. Hüvonen, J. Sichelschmidt, T. S. Yankova, V. N. Glazkov   +5 more
core   +1 more source

Performance Optimization Analysis of Hybrid Excitation Generator With the Electromagnetic Rotor and Embedded Permanent Magnet Rotor for Vehicle [PDF]

, 2021
Huihui Geng, Xueyi Zhang, Lanian Tong, Qingzhi Ma, Mingjun Xu, Yufeng Zhang, Lei Wang   +6 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Transport phase diagram and anomalous metallicity in superconducting infinite-layer nickelates

Nature Communications
Despite obvious similarities in their electronic and crystallographic structures, it remains unclear whether the interactions that shape the normal and superconducting (SC) state properties of high-T c cuprates and infinite-layer nickelates (ILNs) have ...
Yu-Te Hsu, Kyuho Lee, Sven Badoux, Caitlin Duffy, Alessandro Cuoghi, Bai Yang Wang, Arwin Kool, Isaac Haïk-Dunn, Harold Y. Hwang, Nigel E. Hussey   +9 more
doaj   +1 more source