Results 91 to 100 of about 913,403 (346)

Acoustic detection in superconducting magnets for performance characterization and diagnostics

, 2014
Quench diagnostics in superconducting accelerator magnets is essential for understanding performance limitations and improving magnet design. Applicability of the conventional quench diagnostics methods such as voltage taps or quench antennas is limited ...
Marchevsky, M., Prestemon, S., Sabbi, G., Wang, X.   +3 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Transport phase diagram and anomalous metallicity in superconducting infinite-layer nickelates

Nature Communications
Despite obvious similarities in their electronic and crystallographic structures, it remains unclear whether the interactions that shape the normal and superconducting (SC) state properties of high-T c cuprates and infinite-layer nickelates (ILNs) have ...
Yu-Te Hsu, Kyuho Lee, Sven Badoux, Caitlin Duffy, Alessandro Cuoghi, Bai Yang Wang, Arwin Kool, Isaac Haïk-Dunn, Harold Y. Hwang, Nigel E. Hussey   +9 more
doaj   +1 more source

¿Una crítica inmanente radical? Entrevista a José Manuel Romero Cuevas

Oxímora. Revista Internacional de Ética y Política, 2016
José Manuel Romero Cuevas (Sanlúcar de Barrameda, 1970) es profesor en la Universidad de Alcalá (Madrid). Se doctoró en la Universidad de Granada (UGR) con una tesis sobre el problema del conocimiento en F.
Jordi Magnet Colomer
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Dialéctica, temporalidad e historicidad en los escritos tempranos de H. Marcuse

Enrahonar: Quaderns de Filosofia, 2019
La interpretación de la dialéctica hegeliana que el joven Marcuse lleva a cabo en sus escritos tempranos «Sobre el problema de la dialéctica I y II» (1930-1931) y Ontología de Hegel y teoría de la historicidad (1932) contrarresta las críticas de ...
Jordi Magnet Colomer
doaj   +1 more source

Prediction of a new efficient permanent magnet SmCoNiFe3

, 2017
We propose a new efficient permanent magnet, SmCoNiFe3, that is a breakthrough development of the well-known SmCo5 prototype. More modern neodymium magnets of the Nd-Fe-B type have an advantage over SmCo5 because of their greater maximum energy products ...
Antropov, V. P., Däne, M., Eriksson, O., Kvashnin, Y., Landa, A., Locht, I. L. M., Pereiro, M., Söderlind, P., Turchi, P. E. A., Åberg, D.   +9 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Life Cycle Assessment of Neodymium-Iron-Boron Magnet-to-Magnet Recycling for Electric Vehicle Motors.

Environmental Science and Technology, 2018
Neodymium-iron-boron (NdFeB) magnets offer the strongest magnetic field per unit volume, and thus, are widely used in clean energy applications such as electric vehicle motors. However, rare earth elements (REEs), which are the key materials for creating
Hongyue Jin, Peter Afiuny, Stephen K Dove, G. Furlan, M. Zakotnik, Yuehwern Yih, J. Sutherland   +6 more
semanticscholar   +1 more source