Results 51 to 60 of about 2,483,253 (348)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Origin and stability of generalized Wigner crystallinity in triangular moiré systems

open access: yesnpj Quantum Materials
Generalized Wigner crystals (GWC) on triangular moiré superlattices, formed from stacking two layers of transition metal chalcogenides, have been observed at multiple fractional fillings [Nature 587, 214–218 (2020), Nat. Phys.
Aman Kumar   +2 more
doaj   +1 more source

Single Crystal Growth of URu2Si2 by the Modified Bridgman Technique

open access: yesCrystals, 2016
We describe a modified Bridgman growth technique to produce single crystals of the strongly correlated electron material URu2Si2 and its nonmagnetic analogue ThRu2Si2.
Andrew Gallagher   +5 more
doaj   +1 more source

Magnetized stars with differential rotation and a differential toroidal field

open access: yes, 2015
We have succeeded in obtaining magnetized equilibrium states with differential rotation and differential toroidal magnetic fields. If an internal toroidal field of a proto-neutron star is wound up from the initial poloidal magnetic field by differential ...
Fujisawa, Kotaro
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations

open access: yesScientific Data
The UltraCortex repository houses magnetic resonance imaging data of the human brain obtained at an ultra-high field strength of 9.4 T. It contains 86 structural MR images with spatial resolutions ranging from 0.6 to 0.8 mm.
Lucas Mahler   +14 more
doaj   +1 more source

Dynamics of the Chiral Magnetic Effect in a weak magnetic field

open access: yes, 2012
We investigate the real-time dynamics of the chiral magnetic effect in quantum electrodynamics (QED) and quantum chromodynamics (QCD). We consider a field configuration of parallel (chromo)electric and (chromo)magnetic fields with a weak perpendicular ...
A. I. Nikishov   +10 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

NMR and biochemical characterization of the interaction between FGFR1 juxtamembrane domain and phospholipids

open access: yesMagnetic Resonance Letters, 2022
Fibroblast growth factor receptors (FGFRs) play an important role in the regulation of cell proliferation, migration and differentiation, while the juxtamembrane domain (JMD) of FGFRs is the key in mediating these transmembrane signal transduction ...
Yunyan Li   +8 more
doaj   +1 more source

Spin Chain with Magnetic Field and Spinning String in Magnetic Field Background

open access: yes, 2006
We analyze the fast-moving string in the magnetic Melvin field background and find that the associated effective Lagrangian of string sigma model describes the spin chain model with external magnetic field.
E. Witten   +3 more
core   +1 more source

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