Results 51 to 60 of about 3,483,501 (307)

A Proper Use of the Adjacent Land‐Based Observatory Magnetic Field Data to Account for the Geomagnetic Disturbances During Offshore Directional Drilling

open access: yesSpace Weather, 2022
Directional drilling in the oil fields relies particularly on the “on‐fly” measurements of the natural magnetic field (measurements while drilling; MWD); the MWD are eventually used to construct the well path.
Mikhail Kruglyakov   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Phase-field modeling of microstructure evolutions in magnetic materials

open access: yesScience and Technology of Advanced Materials, 2008
Recently, the phase-field method has been extended and utilized across many fields of materials science. Since this method can incorporate, systematically, the effect of the coherency induced by lattice mismatch and the applied stress as well as the ...
T. Koyama
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Application of conjugate gradient least squares method in solving magnetic moments of magnetic targets based on magnetic dipole array model

open access: yesAIP Advances
In order to solve the problem of magnetic targets magnetic field modeling, a magnetic dipole array model was established, a modeling inversion equation system was constructed, and the degree of sickness of the solved equation system under different ...
Binjie Lu, Xiaobing Zhang
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A multisource geomagnetic field model incorporating ocean circulation-induced magnetic field

open access: yesEarth and Planetary Physics
The movement of global ocean circulation in the Earth’s main magnetic field generates a measurable induced magnetic field (about 2 nT at geomagnetic satellite altitudes).
HongBo Yao   +4 more
doaj   +1 more source

Modeling magnetic fields using Gaussian processes

open access: yes2013 IEEE International Conference on Acoustics, Speech and Signal Processing, 2013
Starting from the electromagnetic theory, we derive a Bayesian non-parametric model allowing for joint estimation of the magnetic field and the magnetic sources in complex environments. The model is a Gaussian process which exploits the divergence- and curl-free properties of the magnetic field by combining well-known model components in a novel manner.
Niklas Wahlstrom   +3 more
openaire   +3 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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