Results 81 to 90 of about 132,224 (240)

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Ferrites as magnetic fluids for hyperthermia and MRI contrast agents [PDF]

AIP Conference Proceedings, 2016
Magnetic nanoparticles are currently investigated due to their potential biomedical applications as imaging, therapeutic or theranostic agents. Among the magnetic materials, ferrites possess various advantages. The main one is the ample diversity of preparation methodologies, which allow to tailor their magnetic properties.
Fernando Arteaga-Cardona, Silvia Hidalgo-Tobón, Umapada Pal, Miguel Ángel Méndez-Rojas   +3 more
openaire   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Development and characterization of microfluidic chips with thermal properties employing magnetic hyperthermia [PDF]

EPJ Web of Conferences
There are many fields, such as microfluidics and Organ-on-a-chip technologies, where an optimal setting and control of temperature is necessary. These fields are reaching the forefront of personalised medicine, thus requiring developing more complex ...
Paramés-Estévez Santiago, Radziunas-Salinas Yago, García-Acevedo Pelayo, Piñeiro-Redondo Yolanda, Rivas José, Munuzuri Alberto Pérez, Flores-Arias María Teresa   +6 more
doaj   +1 more source

Influence of alternating magnetic field on non-newtonian blood perfusion and transport of nanoparticles in tissues with embedded blood vessel during hyperthermia

Ain Shams Engineering Journal, 2023
In this paper, we consider the impact of an alternating magnetic field on axisymmetric non-Newtonian nanofluid flow and nanoparticle (magnetite or iron-platinum) transport through a blood vessel and surrounding tissue during hyperthermia therapy.
Sreedhara Rao Gunakala, Victor M. Job, P.V.S.N. Murthy, Sateesh Sakhamuri   +3 more
doaj   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

Photothermal Amplification via Nanorobotic Swarming Dynamics

Advanced Science, EarlyView.
This study explores a novel approach to enhance photothermal therapy using magnetically regulated microswarms. It details the development of magnetic nanoparticles organized into dynamic structures that improve heat retention and conversion efficiency.
Qinglong Wang, Lin Su, Zhengxin Yang, Yihang Jiang, Haojin Yang, Qianqian Wang, Li Zhang, Ben Wang, Jiajia Wang   +8 more
wiley   +1 more source

Experimental determination of the frequency and field dependence of Specific Loss Power in Magnetic Fluid Hyperthermia

, 2017
Magnetic nanoparticles are promising systems for biomedical applications and in particular for Magnetic Fluid Hyperthermia, a therapy that utilizes the heat released by such systems to damage tumor cells.
Innocenti, C., M. Corti, C. Sangregorio, C. Innocenti, Arosio, P., Sangregorio, C., M. Avolio, Guerrini, A., Cobianchi, M., Corti, M., A. Guerrini, F. Orsini, Lascialfari, A., P. Arosio, Orsini, F., Avolio, M., AVOLIO, MATTEO, M. Cobianchi, A. Lascialfari   +18 more
core   +2 more sources

Investigating the effect of magnetic field and nanoparticles characteristics in the treatment of glioblastoma by magnetic hyperthermia method: An in silico study

Results in Engineering
This study investigated the use of magnetic fluid hyperthermia (MFH) for treating glioblastoma multiforme (GBM), a deadly and treatment-resistant tumor. It considers the effects of magnetic nanoparticle (MNP) (different sizes and materials), alternating ...
Yasaman Mozhdehbakhsh Mofrad, Sasan Asiaei, Hossein Shaygani, Seyedeh Sarah Salehi   +3 more
doaj   +1 more source

An exhaustive scrutiny to amplify the heating prospects by devising a core@shell nanostructure for constructive magnetic hyperthermia applications

Scientific Reports, 2023
An interfacial integration at the nanoscale domain through a core@shell (CS) nanostructure has constructively unbarred a wide dimension to researchers on biomedical applications, especially for magnetic fluid hyperthermia.
S. P. Tsopoe, C. Borgohain, Manoranjan Kar, Shantanu Kumar Panda, J. P. Borah   +4 more
doaj   +1 more source