Results 1 to 10 of about 3,374,250 (258)

THC Prevents MDMA Neurotoxicity in Mice. [PDF]

open access: yesPLoS ONE, 2010
The majority of MDMA (ecstasy) recreational users also consume cannabis. Despite the rewarding effects that both drugs have, they induce several opposite pharmacological responses.
Clara Touriño   +2 more
doaj   +1 more source

Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses

open access: yesFrontiers in Oncology, 2020
Moderate hyperthermia at temperatures between 40 and 44°C is a multifaceted therapeutic modality. It is a potent radiosensitizer, interacts favorably with a host of chemotherapeutic agents, and, in combination with radiotherapy, enforces immunomodulation
Niloy R. Datta   +4 more
doaj   +1 more source

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

open access: yesTumor Biology, 2017
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise biochemical mechanisms involved are not clear. This study was carried out to investigate whether mild hyperthermia sensitizes gastric cancer cells to chemotherapy through ...
Ming-Chen Ba   +6 more
doaj   +1 more source

Inducible protective processes in animal systems XV: Hyperthermia enhances the Ethyl methanesulfonate induced adaptive response in meiotic cells of grasshopper Poecilocerus pictus

open access: yesEgyptian Journal of Medical Human Genetics, 2016
Purpose: To understand the role of hyperthermia in adaptive response, Ethyl methanesulfonate (EMS) an anticarcinogenic agent, adapted meiotic cells of Poecilocerus pictus was used.
R. Venu   +3 more
doaj   +1 more source

Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protection.

open access: yesPLoS ONE, 2014
This study describes the sensitization mechanism to thermal stress by histone deacetylase inhibitors (HDACIs) in lung cancer cells and shows that Ku70, based on its acetylation status, mediates the protection of lung cancer from hyperthermia (42.5°C, 1-6
Mohamed K Hassan   +7 more
doaj   +1 more source

The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride

open access: yesFrontiers in Molecular Neuroscience, 2022
Methamphetamine (METH) abuse causes irreversible damage to the central nervous system and leads to psychiatric symptoms including depression. Notably, METH-induced hyperthermia is a crucial factor in the development of these symptoms, as it aggravates ...
Xintao Wang   +28 more
doaj   +1 more source

Decrease in MAP3Ks expression enhances the cell death caused by hyperthermia

open access: yesInternational Journal of Hyperthermia, 2022
Purpose Hyperthermia is a promising anticancer treatment modality. However, the molecular mechanism underlying the thermal sensitivity of tumor cells is largely unknown.
Atsushi Enomoto   +6 more
doaj   +1 more source

Enhancing Gastric Cancer Therapeutic Efficacy through Synergistic Cotreatment of Linderae Radix and Hyperthermia in AGS Cells

open access: yesBiomedicines, 2023
Gastric cancer remains a global health threat, particularly in Asian countries. Current treatment methods include surgery, chemotherapy, and radiation therapy.
Chae-Ryeong Ahn, Seung-Ho Baek
doaj   +1 more source

Graphene Oxide Nanosheets for Localized Hyperthermia—Physicochemical Characterization, Biocompatibility, and Induction of Tumor Cell Death

open access: yesCells, 2020
Background: The main goals of cancer treatment are not only to eradicate the tumor itself but also to elicit a specific immune response that overcomes the resistance of tumor cells against chemo- and radiotherapies. Hyperthermia was demonstrated to chemo-
Malgorzata J. Podolska   +8 more
doaj   +1 more source

Evaluation of The Combined Effects of Hyperthermia, Cobalt-60 Gamma Rays and IUdR on Cultured Glioblastoma Spheroid Cells and Dosimetry Using TLD-100 [PDF]

open access: yesCell Journal, 2014
Objective: In radiation treatment, the irradiation which is effective enough to control the tumors far exceeds normal-tissues tolerance. Thus to avoid such unfavourable outcomes, some methods sensitizing the tumor cells to radiation are used ...
Ali Neshasteh-Riz   +2 more
doaj  

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