Results 21 to 30 of about 40,180 (167)

Lipopolysaccharide potentiates hyperthermia‐induced seizures [PDF]

Brain and Behavior, 2015
AbstractBackgroundProlonged febrile seizures (FS) have both acute and long‐lasting effects on the developing brain. Because FS are often associated with peripheral infection, we aimed to develop a preclinical model of FS that simulates fever and immune activation in order to facilitate the implementation of targeted therapy after prolonged FS in young ...
Eun, Baik-Lin, Abraham, Jayne, Mlsna, Lauren, Kim, Min Jung, Koh, Sookyong   +4 more
openaire   +2 more sources

Uridine-induced hyperthermia in the rabbit

Journal of Pharmacy and Pharmacology, 1986
Abstract Uridine injection in 0.6% saline elevated rabbit temperatures (mean = 0.9 °C) in the USP XX pyrogen test. Hyperthermia was delayed in onset and peaking 3–4 h post injection, but the injection was negative in the limulus amoebocyte lysate (LAL) assay.
J C, Cradock, B R, Vishnuvajjala, T F, Chin, H D, Hochstein, S K, Ackerman   +4 more
openaire   +2 more sources

Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture

Scientific Reports, 2021
Hypoxia and hyperthermia, which can be induced by high environmental temperature or strenuous exercise, are two common stressors that affect intestinal epithelial integrity and lead to multiple clinical symptoms.
Puqiao Lian, Saskia Braber, Soheil Varasteh, Harry J. Wichers, Gert Folkerts   +4 more
doaj   +1 more source

Carbon-coated magnetic particles increase tissue temperatures after laser irradiation [PDF]

Journal of Innovative Optical Health Sciences, 2015
Purpose: This work focused on the investigation the hyperthermia performance of the carbon-coated magnetic particles (CCMPs) in laser-induced hyperthermia.
Shupeng Liu, Na Chen, Fufei Pang, Zhengyi Chen, Tingyun Wang   +4 more
doaj   +1 more source

Severe Hyperthermia Induces Apoptosis Mediated by Caspases Activation and Suppression of Hsp90-alpha Expression in Osteosarcoma Cells

Indonesian Biomedical Journal, 2019
BACKGROUND: Hyperthermia is used as an adjuvant treatment to sensitize cancer cells to subsequent radiotheraphy or chemotherapy. The aim of this study was to study the effect of severe hyperthermia on osteosarcoma cells and its underlying causes ...
Mohammed Ali Nashiry, Gabriele Ruth Anisah Froemming, Yeap Swee Keong, Aletza Binti Mohd Ismail, Aisha Mohd Din, Alyaa Mahmood Al-Khateeb   +5 more
doaj   +1 more source

THC Prevents MDMA Neurotoxicity in Mice. [PDF]

PLoS ONE, 2010
The majority of MDMA (ecstasy) recreational users also consume cannabis. Despite the rewarding effects that both drugs have, they induce several opposite pharmacological responses.
Clara Touriño, Andreas Zimmer, Olga Valverde   +2 more
doaj   +1 more source

Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses

Frontiers in Oncology, 2020
Moderate hyperthermia at temperatures between 40 and 44°C is a multifaceted therapeutic modality. It is a potent radiosensitizer, interacts favorably with a host of chemotherapeutic agents, and, in combination with radiotherapy, enforces immunomodulation
Niloy R. Datta, H. Petra Kok, Hans Crezee, Udo S. Gaipl, Stephan Bodis   +4 more
doaj   +1 more source

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

Tumor Biology, 2017
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise biochemical mechanisms involved are not clear. This study was carried out to investigate whether mild hyperthermia sensitizes gastric cancer cells to chemotherapy through ...
Ming-Chen Ba, Hui Long, Shu-Zhong Cui, Yuan-Feng Gong, Zhao-Fei Yan, Shuai Wang, Yin-Bing Wu   +6 more
doaj   +1 more source

Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protection.

PLoS ONE, 2014
This study describes the sensitization mechanism to thermal stress by histone deacetylase inhibitors (HDACIs) in lung cancer cells and shows that Ku70, based on its acetylation status, mediates the protection of lung cancer from hyperthermia (42.5°C, 1-6
Mohamed K Hassan, Hidemichi Watari, Alaa-Eldin Salah-Eldin, Ahmed S Sultan, Zainab Mohamed, Yoichiro Fujioka, Yusuke Ohba, Noriaki Sakuragi   +7 more
doaj   +1 more source

The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride

Frontiers in Molecular Neuroscience, 2022
Methamphetamine (METH) abuse causes irreversible damage to the central nervous system and leads to psychiatric symptoms including depression. Notably, METH-induced hyperthermia is a crucial factor in the development of these symptoms, as it aggravates ...
Xintao Wang, Xintao Wang, Xintao Wang, Bonan Tong, Bonan Tong, Bonan Tong, Rongji Hui, Rongji Hui, Rongji Hui, Congcong Hou, Congcong Hou, Congcong Hou, Zilu Zhang, Ludi Zhang, Ludi Zhang, Ludi Zhang, Bing Xie, Bing Xie, Bing Xie, Zhiyu Ni, Bin Cong, Bin Cong, Bin Cong, Chunling Ma, Chunling Ma, Chunling Ma, Di Wen, Di Wen, Di Wen   +28 more
doaj   +1 more source