Results 11 to 20 of about 40,180 (167)

AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells

Brazilian Journal of Medical and Biological Research, 2013
Hyperthermia is one of the most effective adjuvant treatments for various cancers with few side effects. However, the underlying molecular mechanisms still are not known. N-myc downstream-regulated gene 2 (NDRG2), a tumor suppressor, has been shown to be
Yurong Tao, Yan Guo, Wenchao Liu, Jian Zhang, Xia Li, Lan Shen, Yi Ru, Yan Xue, Jin Zheng, Xinping Liu, Jing Zhang, Libo Yao   +11 more
doaj   +3 more sources

Intra-peritoneal hyperthermia combining α-galactosylceramide in the treatment of ovarian cancer. [PDF]

PLoS ONE, 2013
The purpose of this study was to investigate the anti-tumor effect and potential mechanisms of i.p. hyperthermia in combination with α-galactosylceramide (α-GalCer) for the treatment of ovarian cancer.
Chao-Chih Wu, Yin-Ting Chuang, Yun-Ting Hsu, Jung-Tang Huang, T-C Wu, Chien-Fu Hung, Yuh-Cheng Yang, Chih-Long Chang   +7 more
doaj   +1 more source

Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization

Cells, 2020
Hyperthermia has been used as an adjuvant treatment for radio- and chemotherapy for decades. In addition to its effects on perfusion and oxygenation of cancer tissues, hyperthermia can enhance the efficacy of DNA-damaging treatments such as radiotherapy ...
Artem V. Luzhin, Bogdan Avanesyan, Artem K. Velichko, Victoria O. Shender, Natalia Ovsyannikova, Georgij P. Arapidi, Polina V. Shnaider, Nadezhda V. Petrova, Igor I. Kireev, Sergey V. Razin, Omar L. Kantidze   +10 more
doaj   +1 more source

A Rare Case of Drug Interaction Presenting as Perioperative Hyperthermia in a Patient Presenting for Neurosurgery

Journal of Neuroanaesthesiology and Critical Care, 2022
Perioperative hyperthermia has many differential diagnoses. This case report describes the rare causation of perioperative hyperthermia in a patient presenting for epilepsy surgery.
Sapna Suresh, Ajay P. Hrishi, Manikandan Sethuraman   +2 more
doaj   +1 more source

Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers

Cell Reports, 2016
Even though hyperthermia is a promising treatment for cancer, the relationship between specific temperatures and clinical benefits and predictors of sensitivity of cancer to hyperthermia is poorly understood.
Hiroto Hatakeyama, Sherry Y. Wu, Yasmin A. Lyons, Sunila Pradeep, Wanqin Wang, Qian Huang, Karem A. Court, Tao Liu, Song Nie, Cristian Rodriguez-Aguayo, Fangrong Shen, Yan Huang, Takeshi Hisamatsu, Takashi Mitamura, Nicholas Jennings, Jeajun Shim, Piotr L. Dorniak, Lingegowda S. Mangala, Marco Petrillo, Vladislav A. Petyuk, Athena A. Schepmoes, Anil K. Shukla, Madeline Torres-Lugo, Ju-Seog Lee, Karin D. Rodland, Anna Fagotti, Gabriel Lopez-Berestein, Chun Li, Anil K. Sood   +28 more
doaj   +1 more source

Effect of hyperthermia-induced hyperventilation on central fatigue during exercise in heat

Journal of Physical Fitness and Sports Medicine, 2012
Exercise endurance is reduced by heat. Among several factors that influence exercise performance is central fatigue, which appears to be caused by an increase in brain temperature.
Keiji Hayashi
doaj   +1 more source

ROS and Sympathetically mediated Mitochondria activation in Brown Adipose Tissue contributes to Methamphetamine-induced hyperthermia

Frontiers in Endocrinology, 2013
Methamphetamine abuse has been shown to induce alterations in mitochondrial function in the brain as well as to induce hyperthermia, which contributes to neurotoxicity and Meth-associated mortality. Brown adipose tissue (BAT), a thermogenic site known to
Manuel eSanchez-Alavez, Bruno eConti, Malcolm Robert Wood, Nikki eBortell, Eduardo Alejandro Bustamante, Enrique eSaez, Howard S Fox, Maria Cecilia G Marcondes   +7 more
doaj   +1 more source

Intraoperative tourniquet-induced hyperthermia in a pediatric patient: a forgotten association -a case report- [PDF]

Korean Journal of Anesthesiology
Background The intraoperative use of tourniquets is associated with several complications, including hyperthermia. We present the first documented case of tourniquet-induced hyperthermia in a pediatric patient at our institution. Case A 5-year-old female
Tarek Tageldin, Muhammad Jaffar Khan, Temur Baykuziyev, Haitham Ahmed   +3 more
doaj   +1 more source

Ventilatory response to increasing body temperature: Characteristics and effect on central fatigue

Journal of Physical Fitness and Sports Medicine, 2015
More than a hundred years ago, it was first reported that increases in body temperature stimulate minute ventilation. Since then, the characteristics, mechanisms and physiological meaning of this ventilatory response to increasing body temperature, so ...
Keiji Hayashi
doaj   +1 more source

Transcriptome analysis of neonatal larvae after hyperthermia-induced seizures in the contractile silkworm, Bombyx mori. [PDF]

PLoS ONE, 2014
The ability to respond quickly and efficiently to transient extreme environmental conditions is an important property of all biota. However, the physiological basis of thermotolerance in different species is still unclear.
Hongyi Nie, Chun Liu, Yinxia Zhang, Mengting Zhou, Xiaofeng Huang, Li Peng, Qingyou Xia   +6 more
doaj   +1 more source