Results 11 to 20 of about 7,634,819 (349)

The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. [PDF]

open access: yesPLoS ONE, 2013
A combination of hyperthermia with radiotherapy and chemotherapy for various solid tumors has been practiced clinically. However, hyperthermic therapy has side effects, such as thrombocytopenia.
Zhicheng Wang   +5 more
doaj   +2 more sources

Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms. [PDF]

open access: yesACS Appl Mater Interfaces, 2022
Superparamagnetic iron oxide nanoparticles (SPIONs) generate heat upon exposure to an alternating magnetic field (AMF) which has been studied for hyperthermia treatment and triggered drug release.
Ansari SR   +6 more
europepmc   +4 more sources

MALIGNANT HYPERTHERMIA INDUCED BY CURARE [PDF]

open access: yesSurvey of Anesthesiology, 1974
Les auteurs rapportent deux cas d’hyperthermie maligne survenus apres administration de curare. Le premier cas survint chez un garcon de 13 ans opere pour sub-occlusion intestinale secondaire a un volvulus, et le second chez un garconnet de 8 ans opere pour appendicite aigue.
B A, Britt, G E, Webb, C, LeDuc
openaire   +2 more sources

Local Temperature Increments and Induced Cell Death in Intracellular Magnetic Hyperthermia

open access: yesACS Nano, 2023
The generation of temperature gradients on nanoparticles heated externally by a magnetic field is crucially important in magnetic hyperthermia therapy. But the intrinsic low heating power of magnetic nanoparticles, at the conditions allowed for human use,
Yuanyu Gu   +14 more
semanticscholar   +1 more source

Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis.

open access: yesPharmacology and Therapeutics, 2020
Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect.
A. Garami   +14 more
semanticscholar   +1 more source

Drug-Induced Hyperthermia Review

open access: yesCureus, 2022
Humans maintain core body temperature via a complicated system of physiologic mechanisms that counteract heat/cold fluctuations from metabolism, exertion, and the environment. Overextension of these mechanisms or disruption of body temperature homeostasis leads to bodily dysfunction, culminating in a syndrome analogous to exertional heat stroke (EHS ...
Horseman, Michael   +12 more
openaire   +2 more sources

Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

open access: yesiScience, 2022
Summary: Hyperthermia inhibits DNA double-strand break (DSB) repair that utilizes homologous recombination (HR) pathway by a poorly defined mechanism(s); however, the mechanisms for this inhibition remain unclear.
Sharmistha Chakraborty   +25 more
doaj   +1 more source

Hyperthermia Induces Apoptosis of 786-O Cells through Suppressing Ku80 Expression. [PDF]

open access: yesPLoS ONE, 2015
Hyperthermia as an anticancer method has been paid increasing attention in recent years. Several studies have shown that hyperthermia can kill tumor cells by inducing apoptosis.
Defeng Qi   +6 more
doaj   +1 more source

CuS-131I-PEG Nanotheranostics-Induced “Multiple Mild-Hyperthermia” Strategy to Overcome Radio-Resistance in Lung Cancer Brachytherapy

open access: yesPharmaceutics, 2022
Brachytherapy is one mainstay treatment for lung cancer. However, a great challenge in brachytherapy is radio-resistance, which is caused by severe hypoxia in solid tumors. In this research, we have developed a PEGylated 131I-labeled CuS nanotheranostics
Yanna Cui   +8 more
doaj   +1 more source

AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells

open access: yesBrazilian Journal of Medical and Biological Research, 2013
Hyperthermia is one of the most effective adjuvant treatments for various cancers with few side effects. However, the underlying molecular mechanisms still are not known. N-myc downstream-regulated gene 2 (NDRG2), a tumor suppressor, has been shown to be
Yurong Tao   +11 more
doaj   +3 more sources

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