Results 41 to 50 of about 40,180 (167)

p-Chloroamphetamine-induced hyperthermia pharmacologically distinct from fenfluramine-induced hyperthermia

Journal of Pharmacy and Pharmacology, 1979
AbstractThe influence of various drug pretreatments upon the responses of rabbits to the putative indirect 5-hydroxytryptamincrgic agonists p-chloroamphetamine (PCA) and fenfluramine were examined. In naive rabbits PCA evoked hyperthermia, behavioural excitation and prominent forepaw clonic activity, while fenfluramine produced only hyperthermia and ...
R M, Quock, B G, Weick
openaire   +2 more sources

Motor performance is preserved in healthy aged adults following severe whole-body hyperthermia

International Journal of Hyperthermia, 2019
Healthy aging is associated with a progressive decline in motor performance and thermoregulatory efficiency. Functional consequences of severe whole-body hyperthermia on neurophysiological functions in healthy aged men have not been investigated.
Marius Brazaitis, Henrikas Paulauskas, Nerijus Eimantas, Laura Daniuseviciute, Gintautas Volungevicius, Albertas Skurvydas   +5 more
doaj   +1 more source

Hyperthermia as a Therapeutic Agent

Journal of Rawalpindi Medical College, 2015
Background: To assess cell death inducing properties of hyperthermia on eye lids of full term Sprague- Dawley rats. Methods: An experimental study was carried out on eyelid of 64 full term Sprague-Dawley rats divided into a control group (A) and an ...
Nabeela Akhtar
doaj  

Berberine Chloride and Hyperthermia Promote Osterix Expression and Suppress Cell Cycle Genes in Osteosarcoma Cells

Yemeni Journal for Medical Sciences, 2018
Objectives: The aim of the current study was to investigate the effects of berberine chloride and various heat conditions on the gene expression of Osterix, RUNX-2, RANKL, CDK2, CDK4, IL-6 and IL-11.
Mohammed Ali Nashiry, Alyaa R Rajih AL-Khateeb, Gabriele Froemming   +2 more
doaj   +1 more source

Cholesterol depletion suppresses thermal necrosis resistance by alleviating an increase in membrane fluidity

Scientific Reports
Thermally resistant cancer cells suppress the therapeutic effects of hyperthermia. However, the mechanism underlying the thermal resistance remains unclear.
Taisei Kanamori, Shogo Yasuda, Runjing Duan, Mei Ohashi, Mai Amou, Kanato Hori, Ryota Tsuda, Taiki Fujimoto, Kenjirou Higashi, Wei Xu, Takuro Niidome, Hiroto Hatakeyama   +11 more
doaj   +1 more source

Post heat shock tolerance: a neuroimmunological anti-inflammatory phenomenon

Journal of Inflammation, 2009
We previously showed that the progression of burn-induced injury was inhibited by exposing the peripheral area of injured skin to sublethal hyperthermia following the burn. We called this phenomenon post-heat shock tolerance.
Jazani Nima, Hassan Zuhair M, Shahabi Shahram   +2 more
doaj   +1 more source

Polyspermy after Induced Hyperthermia in Rats [PDF]

Nature, 1955
IT was reported earlier1 that the incidence of polyspermy in rats increased about seven times if coitus were not permitted at the normal time but delayed until after ovulation. When coitus occurred between 8 and 10 a.m., nearly 9 per cent of the eggs became polyspermic, whereas after normal mating only a little more than 1 per cent were polyspermic ...
openaire   +2 more sources

ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

Journal of Experimental & Clinical Cancer Research
Background In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly understood.
Tao-Yan Lin, Jun-Shuang Jia, Wei-Ren Luo, Xiao-Lin Lin, Sheng-Jun Xiao, Jie Yang, Jia-Wei Xia, Chen Zhou, Zhi-Hao Zhou, Shu-Jun Lin, Qi-Wen Li, Zhi-Zhi Yang, Ye Lei, Wen-Qing Yang, Hong-Fen Shen, Shi-Hao Huang, Sheng-Chun Wang, Lin-Bei Chen, Yu-Lin Yang, Shu-Wen Xue, Yong-Long Li, Guan-Qi Dai, Ying Zhou, Ying-Chun Li, Fang Wei, Xiao-Xiang Rong, Xiao-Jun Luo, Bing-Xia Zhao, Wen-Hua Huang, Dong Xiao, Yan Sun   +30 more
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Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma

Scientific Reports, 2018
In the present study, we have aimed to characterize the intrinsic, extrinsic and ER-mediated apoptotic induction by hyperthermia in an in vitro model of human malignant melanoma and furthermore, to evaluate its therapeutic effectiveness in an adjuvant ...
T. Mantso, S. Vasileiadis, I. Anestopoulos, G. P. Voulgaridou, E. Lampri, S. Botaitis, E. N. Kontomanolis, C. Simopoulos, G. Goussetis, R. Franco, K. Chlichlia, A. Pappa, M. I. Panayiotidis   +12 more
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Comprehensive multi-omics analysis reveals WEE1 as a synergistic lethal target with hyperthermia through CDK1 super-activation

Nature Communications
Hyperthermic intraperitoneal chemotherapy’s role in ovarian cancer remains controversial, hindered by limited understanding of hyperthermia-induced tumor cellular changes.
Xiaohang Yang, Xingyuan Hu, Jingjing Yin, Wenting Li, Yu Fu, Bin Yang, Junpeng Fan, Funian Lu, Tianyu Qin, Xiaoyan Kang, Xucui Zhuang, Fuxia Li, Rourou Xiao, Tingyan Shi, Kun Song, Jing Li, Gang Chen, Chaoyang Sun   +17 more
doaj   +1 more source