Results 61 to 70 of about 534,975 (301)

Flux-loss of buoyant ropes interacting with convective flows [PDF]

, 2001
We present 3-d numerical magneto-hydrodynamic simulations of a buoyant, twisted magnetic flux rope embedded in a stratified, solar-like model convection zone.
Abbett, B. V. Gudiksen, Caligari, Canfield, Cattaneo, Dorch, Dorch, Dorch, Emonet, Emonet, Fan, Fan, Galsgaard, Leighton, Matsumoto, Matthews, Moreno-Insertis, Moreno-Insertis, Nordlund, S. B. F. Dorch, Schüssler, Spruit, Spruit, Sterling, Tobias, Tsinganos, W. P. Abbett, Worden, Å. Nordlund   +28 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Empirical Modeling of Radiative versus Magnetic Flux for the Sun-as-a-Star

, 2010
We study the relationship between full-disk solar radiative flux at different wavelengths and average solar photospheric magnetic-flux density, using daily measurements from the Kitt Peak magnetograph and other instruments extending over one or more ...
Chapman, Gary, Martens, Petrus C. H., Nandy, Dibyendu, Preminger, Dora   +3 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Deep Learning Model for Magnetic Flux Density Prediction in Magnetic Spring on the Vibration Generator

IEEE Access
The magnetic spring placed on vibration generator consists of top and bottom fixed magnets with a third magnet levitated between them. Nonlinear dynamic analysis appears in the magnetic flux density of the magnetic spring activated by the vibration ...
Grazia Lo Sciuto, Joanna Bijak, Zygmunt Kowalik, Pawel Kowol, Rafal Brociek, Giacomo Capizzi   +5 more
doaj   +1 more source

Switchable collective pinning of flux quanta using magnetic vortex arrays

, 2008
We constructed a superconducting/ferromagnetic hybrid system in which the ordering of the pinning potential landscape for flux quanta can be manipulated.
I. F. Lyuksyutov, Ivan K. Schuller, J. D. Jackson, J. E. Villegas, K. D. Smith, L. P. Gor`kov, Lei Huang, M. Lange, R. Morales, V. V. Volkov, Yimei Zhu   +10 more
core   +1 more source

Observations of flux rope formation prior to coronal mass ejections [PDF]

, 2013
Understanding the magnetic configuration of the source regions of coronal mass ejections (CMEs) is vital in order to determine the trigger and driver of these events.
Green, Lucie M., Kliem, Bernhard
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

magnetic flux

, 2014
Citation: 'magnetic flux' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03684 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +2 more sources

Reconnection of magnetic flux ropes driven by two-color Laguerre–Gaussian laser pulses in plasma

Matter and Radiation at Extremes
The generation and reconnection of magnetic flux ropes in a plasma irradiated by two Laguerre–Gaussian laser pulses with different frequencies and opposite topological charges are investigated numerically by particle-in-cell simulations. It is shown that
Yin-Hong Liu, Su-Ming Weng, Zheng-Ming Sheng   +2 more
doaj   +1 more source