Results 71 to 80 of about 381,165 (296)

3D Magnetic Analysis of the CMS Magnet [PDF]

, 2000
The CMS magnetic system consists of a super-conducting solenoid coil, 12.5 m long and 6 m free bore diameter, and of an iron flux-return yoke, which includes the central barrel, two end-caps and the ferromagnetic parts of the hadronic forward calorimeter.
Campi, D., Curé, B., Desirelli, A., Farinon, S., Gerwig, H., Green, D., Grillet, J. P., Hervé, A., Kircher, F., Klyukhin, V. I., Levesy, B., Loveless, R., Smith, R. P.   +12 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Structural Design and Transmission Performance Analysis of Double Modulated Coaxial Magnetic Gear

Jixie chuandong, 2019
Aiming at the problem of low transmission torque caused by the magnetic flux leakage phenomenon of the traditional magnetic gear permanent magnet，a coaxial magnetic gear model with double modulation structure is established based on the relative ...
Peng Wu, Zina Zhu, Kaiyuan Li
doaj  

Signatures of magnetic reconnection at boundaries of interplanetary small-scale magnetic flux ropes

, 2010
The interaction between interplanetary small-scale magnetic flux ropes and the magnetic field in the ambient solar wind is an important topic to understand- ing the evolution of magnetic structures in the heliosphere.
Cartwright, Cheng, Feng, Goldstein, Gopalswamy, Gosling, Hui Tian, Jiansen He, Lundquist, Petschek, Pick, Qiugang Zong, Schwenn, Shiota, Shuo Yao, van der Holst, Yu Qi   +16 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

双层实心异步磁力联轴器三维静态气隙磁场解析计算

Jixie chuandong, 2013
In order to obtain the spatial distribution of the 3-D static air-gap magnetic field in double-layer solid rotor asynchronous magnetic couplings,the 3-D analytical model of the air-gap magnetic field in the coupling is built based on the equivalent ...
杨超君, 徐燕飞, 陈晓平, 杜怿
doaj  

Effect of Finite Larmor Radius on the Cosmic Ray Penetration into an Interplanetary Magnetic Flux Rope

, 2010
We discuss a mechanism for cosmic ray penetration into an interplanetary magnetic flux rope, particularly the effect of the finite Larmor radius and magnetic field irregularities.
Cane, Cane, Giacalone, Hironori Shimazu, Krittinatham, le Roux, Mace, Marubashi, Michałek, Minnie, Munakata, Munakata, Qin, Qin, Qin, Sanderson, Shimazu, Yûki Kubo, Zimbardo   +18 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Safe Distance for Leukemia Risk Due to Magnetic Fields Caused by High-Voltage Power Lines Using Linear Regression Model

International Journal of Environmental Health Engineering
Aim: Power transmission lines are considered sources with extremely low-frequency magnetic fields. According to previous studies, these types of electromagnetic fields impose adverse effects on the human health.
Afsaneh Amiri, Bahram Kamarehie, Mehrdad Gholami, Faramarz Azimi   +3 more
doaj   +1 more source