Results 51 to 60 of about 2,241,461 (303)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Surface discharge characteristics of silicone gel and DBC under positive repetitive square voltage

Power Electronic Devices and Components, 2022
Silicone gel and direct bonded copper (DBC) as the key components of high voltage power devices are widely used in the insulation packaging of high voltage power devices, respectively.
Chao Li, Boyuan Cao, Xuebao Li, Xiangchen Liu, Jinjin Cheng, Zhaocheng Liu, Zhibin Zhao, Zhongguang Yang   +7 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A fabrication process of soft magnetic Ni films electroplated from gel electrolyte

AIP Advances
We have already reported some electroplated magnetic films using aqueous solutions. In the present study, we proposed a fabrication process for electroplated soft magnetic films (Ni films) using gel electrolytes. We added gelatin to the plating baths and
Takeshi Yanai, Yusuke Matsumoto, Kota Shiraki, Runa Hosohata, Yuka Yamaguchi, Akihiro Yamashita, Masaki Nakano, Hirotoshi Fukunaga   +7 more
doaj   +1 more source

Study of magnetic properties of NiZnCu ferrite synthesized by Pechini method and solid-state reactions

AIP Advances, 2018
Ni-Zn-Cu ferrites are exhibiting excellent magnetic properties at large frequencies and are consequently produced as low-loss magnetic materials used for magnetic components in power electronics.
Gaëlla Frajer, Mathieu Salaün, Gérard Delette, Hervé Chazal, Olivier Isnard   +4 more
doaj   +1 more source

Silica Magnetite Adsorbent: Effect of Drying Temperature of Silica Sol Gel on Magnetite Core Structure

Jurnal Kimia Sains dan Aplikasi, 2018
Recently, magnetite was investigated as water purification adsorbent because it’s unique magnetic properties that improved the adsorption efficiency through desorption process.
Choiril Azmiyawati, Endang Sawitri, Parsaoran Siahaan   +2 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Advance effect of magnetic field on the rheological properties of manganese zinc ferrite ferrofluid

Journal of Nigerian Society of Physical Sciences
The rheological characteristics of manganese zinc (Mn-Zn) ferrite magnetic nanofluid synthesized using co-precipitation technique were examined in the absence and presence of magnetic fields.
A. A. Ibiyemi, O. Akinrinola, G. T. Yusuf, S. Olaniyan, J. Lawal, M. Orojo, B. Osuporu   +6 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source