Results 61 to 70 of about 19,729 (215)

Polyethylene glycol-coated porous magnetic nanoparticles for targeted delivery of chemotherapeutics under magnetic hyperthermia condition

International Journal of Hyperthermia, 2019
Purpose: Although magnetite nanoparticles (MNPs) are promising agents for hyperthermia therapy, insufficient drug encapsulation efficacies inhibit their application as nanocarriers in the targeted drug delivery systems.
Ali Dabbagh, Ziba Hedayatnasab, Hamed Karimian, Masoud Sarraf, Chai Hong Yeong, Hamid Reza Madaah Hosseini, Noor Hayaty Abu Kasim, Tin Wui Wong, Noorsaadah Abdul Rahman   +8 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Antitumor magnetic hyperthermia induced by RGD-functionalized Fe3O4 nanoparticles, in an experimental model of colorectal liver metastases

Beilstein Journal of Nanotechnology, 2016
This work reports important advances in the study of magnetic nanoparticles (MNPs) related to their application in different research fields such as magnetic hyperthermia. Nanotherapy based on targeted nanoparticles could become an attractive alternative
Oihane K. Arriortua, Eneko Garaio, Borja Herrero de la Parte, Maite Insausti, Luis Lezama, Fernando Plazaola, Jose Angel García, Jesús M. Aizpurua, Maialen Sagartzazu, Mireia Irazola, Nestor Etxebarria, Ignacio García-Alonso, Alberto Saiz-López, José Javier Echevarria-Uraga   +13 more
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Optimizing magnetic hyperthermia for melanoma: the role of nanoparticle uptake inhibition

Nano Express
Superparamagnetic iron oxide nanoparticles (SPIONs) are widely used in magnetic hyperthermia, where their therapeutic efficacy depends on efficient heat generation.
Beatriz T Simões, Catarina Chaparro, Tânia Vieira, Manuel A Valente, Marco C V Cavaco, Vera Neves, Jorge C Silva, João Paulo Borges, Filipe V Almeida, Paula Soares   +9 more
doaj   +1 more source

Can commercial ferrofluids be exploited in AC magnetic hyperthermia treatment to address diverse biomedical aspects?

EPJ Web of Conferences, 2014
Multifunctional magnetic nanoparticles are considered as promising candidates for various applications combining diagnosis, imaging and therapy. In the present work, we elaborate on the commercial colloidal solution “FluidMAG” (from Chemicell GmbH) as a ...
Angelakeris M., Li Zi-An, Sakellari D., Simeonidis K., Spasova M., Farle M.   +5 more
doaj   +1 more source

Hydroxyapatite Coated Iron Oxide Nanoparticles: A Promising Nanomaterial for Magnetic Hyperthermia Cancer Treatment

Nanomaterials, 2017
Targeting cancer cells without injuring normal cells is the prime objective in treatment of cancer. In this present study, solvothermal and wet chemical precipitation techniques were employed to synthesize iron oxide (IO), hydroxyapatite (HAp), and ...
Sudip Mondal, Panchanathan Manivasagan, Subramaniyan Bharathiraja, Madhappan Santha Moorthy, Van Tu Nguyen, Hye Hyun Kim, Seung Yun Nam, Kang Dae Lee, Junghwan Oh   +8 more
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Metal-organic framework-coated magnetite nanoparticles for synergistic magnetic hyperthermia and chemotherapy with pH-triggered drug release

Science and Technology of Advanced Materials, 2019
In nanoplatform-based tumor treatment, combining chemotherapy with hyperthermia therapy is an interesting strategy to achieve enhanced therapeutic efficacy with low dose of delivery drugs.
Jiajie Chen, Jiaxing Liu, Yaping Hu, Zhengfang Tian, Yufang Zhu   +4 more
doaj   +1 more source

Magnetic and near-infrared derived heating characteristics of dimercaptosuccinic acid coated uniform Fe@Fe3O4 core–shell nanoparticles

Nano Convergence, 2020
Among the number of hyperthermia materials, magnetic nanoparticles have received much attention. In this work, we studied the heating characteristics of uniform Fe@Fe3O4 core–shell nanoparticle under near-infrared laser irradiation and external AC ...
Changhyuk Koo, Hwichan Hong, Pyung Won Im, Hoonsub Kim, Chaedong Lee, Xuanzhen Jin, Bingyi Yan, Wooseung Lee, Hyung-Jun Im, Sun Ha Paek, Yuanzhe Piao   +10 more
doaj   +1 more source