Results 71 to 80 of about 1,701,138 (265)

Polyethylene glycol-coated porous magnetic nanoparticles for targeted delivery of chemotherapeutics under magnetic hyperthermia condition

International Journal of Hyperthermia, 2019
Purpose: Although magnetite nanoparticles (MNPs) are promising agents for hyperthermia therapy, insufficient drug encapsulation efficacies inhibit their application as nanocarriers in the targeted drug delivery systems.
Ali Dabbagh, Ziba Hedayatnasab, Hamed Karimian, Masoud Sarraf, Chai Hong Yeong, Hamid Reza Madaah Hosseini, Noor Hayaty Abu Kasim, Tin Wui Wong, Noorsaadah Abdul Rahman   +8 more
doaj   +1 more source

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang, Nailin Yang, Shuangshuang Ji, Siping Meng, Di Wang, Wenjun Liang, Xuming Bai, Yong Jin, Xingwei Sun   +8 more
wiley   +1 more source

Can commercial ferrofluids be exploited in AC magnetic hyperthermia treatment to address diverse biomedical aspects?

EPJ Web of Conferences, 2014
Multifunctional magnetic nanoparticles are considered as promising candidates for various applications combining diagnosis, imaging and therapy. In the present work, we elaborate on the commercial colloidal solution “FluidMAG” (from Chemicell GmbH) as a ...
Angelakeris M., Li Zi-An, Sakellari D., Simeonidis K., Spasova M., Farle M.   +5 more
doaj   +1 more source

Hybrid supraparticles for combined MPI and magnetic hyperthermia

Combining magnetic particle imaging (MPI) with magnetic hyperthermia in a single location opens new effectivetheranostic applications, e.g. in targeted cancer therapy.
Müssig, Stephan, Kluwe, Bruno, Bakenecker, Anna C., Ackers, Justin, Heinlein, Markus, Mandel, Karl, Bakenecker, Anna Christin, Wei, Huimin, Aderhold, Eric   +8 more
core   +1 more source

Spatial focusing of magnetic particle hyperthermia

Nanoscale Advances, 2020
Magnetic particle hyperthermia is a promising cancer therapy, but a typical constraint of its applicability is localizing heat solely to malignant regions sparing healthy surrounding tissues.
Eirini Myrovali, Nikos Maniotis, Theodoros Samaras, Makis Angelakeris   +3 more
openaire   +3 more sources

Biologically Targeted Magnetic Hyperthermia: Potential and Limitations [PDF]

Frontiers in Pharmacology, 2018
Hyperthermia, the mild elevation of temperature to 40-43°C, can induce cancer cell death and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full potential as a clinically relevant treatment modality has been restricted by its inability to effectively and preferentially heat malignant cells.
David Chang, David Chang, David Chang, May Lim, Jeroen A. C. M. Goos, Jeroen A. C. M. Goos, Ruirui Qiao, Yun Yee Ng, Friederike M. Mansfeld, Friederike M. Mansfeld, Friederike M. Mansfeld, Michael Jackson, Thomas P. Davis, Thomas P. Davis, Maria Kavallaris, Maria Kavallaris   +15 more
openaire   +7 more sources

Targeted Perturbation of Mitochondrial Energy Metabolism via Thermoelectric Nanoflowers for Enhanced Cuproptosis Echoed With Immunotherapy

Advanced Science, EarlyView.
We fabricated a thermoelectric nanomedicine to disrupt the ATP energy supply for the copper transporter ATP7B, thereby enhancing cuproptosis and achieving synergistic immunotherapy for anti‐tumor purposes. The fabricated TBCT NFs can efficiently disrupt the electron transport chain function via superoxide‐induced NADH oxidation, leading to ATP ...
Haoyang Du, Chao Xu, Hao Wang, Bo Peng, Peng Liu, Wei Gao, Tao Ye, Xinyuan Yu, Ying Shi, Jiaxin Liu, Tiancong Zhao, Bin Sun, Piaoping Yang, Manjie Zhang   +13 more
wiley   +1 more source

Antitumor magnetic hyperthermia induced by RGD-functionalized Fe3O4 nanoparticles, in an experimental model of colorectal liver metastases

Beilstein Journal of Nanotechnology, 2016
This work reports important advances in the study of magnetic nanoparticles (MNPs) related to their application in different research fields such as magnetic hyperthermia. Nanotherapy based on targeted nanoparticles could become an attractive alternative
Oihane K. Arriortua, Eneko Garaio, Borja Herrero de la Parte, Maite Insausti, Luis Lezama, Fernando Plazaola, Jose Angel García, Jesús M. Aizpurua, Maialen Sagartzazu, Mireia Irazola, Nestor Etxebarria, Ignacio García-Alonso, Alberto Saiz-López, José Javier Echevarria-Uraga   +13 more
doaj   +1 more source

Hydroxyapatite Coated Iron Oxide Nanoparticles: A Promising Nanomaterial for Magnetic Hyperthermia Cancer Treatment

Nanomaterials, 2017
Targeting cancer cells without injuring normal cells is the prime objective in treatment of cancer. In this present study, solvothermal and wet chemical precipitation techniques were employed to synthesize iron oxide (IO), hydroxyapatite (HAp), and ...
Sudip Mondal, Panchanathan Manivasagan, Subramaniyan Bharathiraja, Madhappan Santha Moorthy, Van Tu Nguyen, Hye Hyun Kim, Seung Yun Nam, Kang Dae Lee, Junghwan Oh   +8 more
doaj   +1 more source

Magnetic and near-infrared derived heating characteristics of dimercaptosuccinic acid coated uniform Fe@Fe3O4 core–shell nanoparticles

Nano Convergence, 2020
Among the number of hyperthermia materials, magnetic nanoparticles have received much attention. In this work, we studied the heating characteristics of uniform Fe@Fe3O4 core–shell nanoparticle under near-infrared laser irradiation and external AC ...
Changhyuk Koo, Hwichan Hong, Pyung Won Im, Hoonsub Kim, Chaedong Lee, Xuanzhen Jin, Bingyi Yan, Wooseung Lee, Hyung-Jun Im, Sun Ha Paek, Yuanzhe Piao   +10 more
doaj   +1 more source