Results 91 to 100 of about 4,186,737 (348)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Improvements of single sheet testers for measurement of 2-D magnetic properties up to high flux density

, 1999
Due to structural limitation, the currently proposed apparatus based on a single sheet tester (SST) cannot measure magnetic properties along arbitrary directions (so-called 2-D magnetic properties) of silicon steel at high flux densities.
Nakano, Masanori, Fujiwara, K., Nishimoto, H., Takahashi, N., Takahashi, Norio, K. Fujiwara, Nishimoto, Hidehiko, Fujiwara, Koji, M. Nakano, H. Nishimoto, N. Takahashi   +10 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Magnetic Stability Analysis for the Geodynamo [PDF]

, 2004
Kinematic dynamo modelling addresses the growth of magnetic fields under the action of fluid flow, effected in the geophysical case by the action of the convecting electrically conducting outer core and magnetic diffusion. In this study, we prescribe the
Livermore, Philip
core  

A neurodynamical model of brightness induction in V1 [PDF]

, 2013
Brightness induction is the modulation of the perceived intensity of an area by the luminance of surrounding areas. Recent neurophysiological evidence suggests that brightness information might be explicitly represented in V1, in contrast to the more ...
Otazu, Xavier, Olivier Penacchio, Laura Dempere-Marco, Xavier Otazu, Xavier Otazu (414596), Dempere-Marco Laura, Otazu Porter, Xavier, Penacchio Olivier, Laura Dempere-Marco (139148), Dempere-Marco, Laura, Olivier Penacchio (414595), Penacchio, Olivier, Otazu Xavier   +12 more
core   +1 more source

Engineered Porous Nanocomposites That Deliver Remarkably Low Carbon Capture Energy Costs

Cell Reports Physical Science, 2020
Summary: A key barrier to the use of carbon dioxide capture technologies is the operating energy requirement, the chief contributor being the energy required to regenerate the capture media.
Muhammad Munir Sadiq, Kristina Konstas, Paolo Falcaro, Anita J. Hill, Kiyonori Suzuki, Matthew R. Hill   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

magnetic induction

, 2019
Citation: 'magnetic induction' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03687 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source