Results 71 to 80 of about 4,186,737 (348)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Magnetic induction mapping of magnetite chains in magnetotactic bacteria at room temperature and close to the Verwey transition using electron holography

open access: yes, 2005
Off-axis electron holography in the transmission electron microscope is used to record magnetic induction maps of closely spaced magnetite crystals in magnetotactic bacteria at room temperature and after cooling the sample using liquid nitrogen.
Harrison, R. J.   +5 more
core   +1 more source

On the variation with flux and frequency of the core loss coefficients in electrical machines [PDF]

open access: yes, 2006
A model of core losses, in which the hysteresis coefficients are variable with the frequency and induction (flux density) and the eddy-current and excess loss coefficients are variable only with the induction, is proposed. A procedure for identifying the
Dellinger, S.J.   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Non-dimensional design approach for electrodynamic bearings [PDF]

open access: yes, 2012
Electrodynamic bearings (EDBs) are passive magnetic bearings that exploit the interaction between eddy currents developed in a rotating conductor and a static magnetic field to generate forces. Similar to other types of magnetic suspensions, EDBs provide
Impinna, Fabrizio   +4 more
core  

3D Neuromorphic Wireless Power Transfer and Energy Transmission Based Synaptic Plasticity

open access: yesIEEE Access, 2019
Energy consumption combined with scalability and 3D architecture is a fundamental constraint for brain-inspired computing. Neuromorphic architectures including memristive, spintronic, and floating gate metal-oxide-semiconductors achieve energy efficiency
Burhan Gulbahar
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Single‐ and Multi‐Pass Magnetometric Subsurface Ocean Detection and Characterization in Icy Worlds Using Principal Component Analysis (PCA): Application to Triton

open access: yesEarth and Space Science, 2022
Many moons in the solar system are thought to potentially harbor hidden oceans based on the features observed at their surfaces. However, the magnetic induction signatures measured in the vicinity of these moons provide the most compelling evidence for ...
C. J. Cochrane   +9 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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