Results 51 to 60 of about 883,127 (312)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Excellent ferroelectricity of 50 nm-thick doped HfO2 thin films induced by annealing with a rapid-heating-temperature process

AIP Advances, 2020
The ferroelectric HfO2 thin film has attracted a lot of research interest due to being Pb free and its excellent compatibility with the Si-based semiconductor process.
Zhiyong Quan, Meimei Wang, Xiao Zhang, Huihui Liu, Wei Zhang, Xiaohong Xu   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Hydrogen‐Associated Filling‐Controlled Mottronics Within Thermodynamically Metastable Vanadium Dioxide

Advanced Science
The discovery of hydrogen‐associated topotactic phase modulations in correlated oxide system has emerged as a promising paradigm to explore exotic electronic states and physical functionality. Here hydrogen‐induced Mott phase transitions are demonstrated
Xuanchi Zhou, Yongjie Jiao, Wentian Lu, Jinjian Guo, Xiaohui Yao, Jiahui Ji, Guowei Zhou, Huihui Ji, Zhe Yuan, Xiaohong Xu   +9 more
doaj   +1 more source

Conductive single-phase SrMoO3 epitaxial films synthesized in pure Ar ambience via plasma-assisted radio frequency sputtering

Science and Technology of Advanced Materials
The cubic perovskite SrMoO3 with a paramagnetic ground state and remarkably low room-temperature resistivity has been considered as a suitable candidate for the new-era oxide-based technology. However, the difficulty of preparing single-phase SrMoO3 thin
Mouli Roy-Chowdhury, Cong He, Ke Tang, Hiroki Koizumi, Zhenchao Wen, Subhash Thota, Hiroaki Sukegawa, Tadakatsu Ohkubo, Seiji Mitani   +8 more
doaj   +1 more source

Microstructure, magnetic and magnetocaloric properties in Ni42.9Co6.9Mn38.3Sn11.9 alloy ribbons

AIP Advances, 2018
The microstructure, magnetic and magnetocaloric properties are investigated in the melt-spun and annealed Ni42.9Co6.9Mn38.3Sn11.9 ribbons. The columnar grains grow perpendicular to ribbon surfaces.
S. C. Ma, Q. Ge, S. Yang, K. Liu, X. Q. Han, K. Yu, Y. Song, Z. S. Zhang, Q. Z. Jiang, C. C. Chen, R. H. Liu, Z. C. Zhong   +11 more
doaj   +1 more source

Poly-para-xylylene enhanced Fe-based amorphous powder cores with improved soft magnetic properties via chemical vapor deposition

Materials & Design, 2020
In this work, dense and pinhole-free poly-para-xylylene (PPX) with high thermal stability, high insulating property and high lubricity has been designed as coating layer for Fe-based amorphous powder.
Yiqun Zhang, Yaqiang Dong, Bang Zhou, Qiang Chi, Liang Chang, Mengji Gong, Jianjun Huang, Yan Pan, Aina He, Jiawei Li, Xinmin Wang   +10 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Characterization and Magnetic Properties of Sintered Glass-Ceramics from Dispersed Fly Ash Microspheres

, 2023
The recycling of hazardous industrial waste into high-tech materials with desired properties is of considerable interest since it provides optimal alternatives for its final disposal.
Sergey V. Semenov, Leonid A. Solovyov, Elena V. Fomenko, Yuriy V. Knyazev, Vladimir V. Yumashev, Galina V. Akimochkina, Alexander G. Anshits   +6 more
core   +1 more source

Imaging and Linking Spatial Magnetic Nanoparticle Distribution to Microbead Torques Using Soft X‐Ray Laminography

Advanced Physics Research
The introduction of magnetic microbeads has greatly advanced biomedical research by enabling high‐precision methods for cell sorting, biomolecule transport, and cell force analysis.
Findan Block, Finn Klingbeil, Dennis Seidler, Christine Arndt, Sandra Sindt, Katharina Witte, Benjamin Watts, Jörg Raabe, Christine Selhuber‐Unkel, Jeffrey McCord   +9 more
doaj   +1 more source