Results 61 to 70 of about 1,759,230 (286)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Improved magnetic properties and thermal stabilities of Pr-Nd-Fe-B sintered magnets by Hf addition

AIP Advances, 2018
Nd2Fe14B-type permanent magnets have been widely applied in various fields such as wind power, voice coil motors, and medical instruments. The large temperature dependence of coercivity, however, limits their further applications.
Qingzheng Jiang, Weikai Lei, Qingwen Zeng, Qichen Quan, Lili Zhang, Renhui Liu, Xianjun Hu, Lunke He, Zhiqi Qi, Zhihua Ju, Minglong Zhong, Shengcan Ma, Zhenchen Zhong   +12 more
doaj   +1 more source

Intrinsic vacancy in 2D defective semiconductor In2S3 for artificial photonic nociceptor

Materials Futures, 2023
It is crucial to develop an advanced artificially intelligent optoelectronic information system that accurately simulates photonic nociceptors like the activation process of a human visual nociceptive pathway.
Peng Wang, Wuhong Xue, Wenjuan Ci, Ruilong Yang, Xiaohong Xu   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Emergence of sliding ferroelectricity in naturally parallel-stacked multilayer ReSe2 semiconductor

Nature Communications
Sliding ferroelectric semiconductors can advance the applications of slidetronics in silicon-compatible microelectronic and optoelectronic devices for the post-Moore era.
Wuhong Xue, Peng Wang, Wenjuan Ci, Ying Guo, Jingyuan Qu, Zeting Zeng, Tianqi Liu, Ri He, Shaobo Cheng, Xiaohong Xu   +9 more
doaj   +1 more source

Systematic investigation on transverse thermoelectric conversion of RE2(Fe,Co)14B (RE = rare-earth) compounds

Science and Technology of Advanced Materials
Transverse thermoelectric generation (TEG) based on the anomalous Nernst effect (ANE) is a promising technology capable of converting waste heat into electricity.
Babu Madavali, Fuyuki Ando, Takamasa Hirai, Andres Martin-Cid, Ken-ichi Uchida, Hossein Sepehri-Amin   +5 more
doaj   +1 more source

Spin-dependent Transport Properties of CrO2 Micro Rod

Nano-Micro Letters, 2014
The CrO2 micro rod powder was synthesized by decomposing the CrO3 flakes at a specific temperature to yield precursor and annealing such a precursor in a sealed glass tube.
Zhen Wang, Li Xi, Yikai Yang, Yue Li, Xuemeng Han, Yalu Zuo, Jianbo Wang   +6 more
doaj   +1 more source

Tunable Emergent Heterostructures in a Prototypical Correlated Metal

, 2018
At the interface between two distinct materials desirable properties, such as superconductivity, can be greatly enhanced, or entirely new functionalities may emerge.
A. Podlesnyak, A. Sazonov, C. D. Batista, D. M. Fobes, E Dagotto, E. D. Bauer, F Ronning, F. Ronning, G Ehlers, G. Ehlers, H Boschker, H Suwa, J. D. Thompson, JF Ge, JK Glasbrenner, L Jiao, L. W. Harriger, M. Janoschek, N Reyren, N. J. Ghimire, P Das, Pinaki Das, PJW Moll, R. I. Bewley, RA Borzi, S Raymond, S. Zhang, S.-Z. Lin, SA Kivelson, SH Baek, T Park, T Park, T Willers, TM Chuang, V. Hutanu, W Selke, ZI Alferov   +36 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Reduced hysteresis in La0.7Ce0.3Fe11.5Si1.5 hydrides by grain size reduction

Science and Technology of Advanced Materials
Magnetic cooling technology, based on the magnetocaloric effect (MCE), offers an energy-efficient and eco-friendly alternative to conventional gas compression, but is often hindered by large magnetic hysteresis, which limits cyclic performance.
Mitali Madhusmita Prusty, Sri Harsha Molleti, Hiroto Takanobu, Sai Rama Krishna Malladi, Xin Tang, Hossein Sepehri-Amin   +5 more
doaj   +1 more source