Results 41 to 50 of about 197,485 (261)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluation of column studies using Cynodon dactylon plant‐mediated amino‐grouped silica‐layered magnetic nanoadsorbent to remove noxious hexavalent chromium metal ions

IET Nanobiotechnology, 2021
Magnetic nanoparticles are desirable adsorbents because of their unique superparamagnetic nature with the enhanced binding specificity and surface material interaction.
Dhanya Vishnu, Balaji Dhandapani
doaj   +1 more source

Quasi-two-dimensional Brownian dynamics simulations on the aggregation phenomena of a cubic magnetic particle suspension in a rotating magnetic field

Nihon Kikai Gakkai ronbunshu, 2021
In the present study, we have addressed a suspension composed of magnetic cubic particles in a rotating magnetic field by means of quasi-two-dimensional Brownian dynamics simulations in order to investigate the dependence of the regime change on a ...
Kazuya OKADA, Akira SATOH
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Collisions and dynamics of particles with magnetic dipole moment and electric charge near magnetized rotating Kerr black holes

European Physical Journal C: Particles and Fields
Analysis of test magnetized and charged particles around black holes immersed in external magnetic fields may help to explain the observed astrophysical phenomena related to black holes, such as the acceleration of particles up to high energies.
Shokhzod Jumaniyozov, Saeed Ullah Khan, Javlon Rayimbaev, Ahmadjon Abdujabbarov, Bobomurat Ahmedov   +4 more
doaj   +1 more source

Magnetic Nanoparticle Sensors

Sensors, 2009
Many types of biosensors employ magnetic nanoparticles (diameter = 5–300 nm) or magnetic particles (diameter = 300–5,000 nm) which have been surface functionalized to recognize specific molecular targets.
Isaac Koh, Lee Josephson
doaj   +1 more source

Role of Ionic Liquids in Composites in Analytical Sample Preparation

Separations, 2020
Ionic liquids (ILs) are a group of non-conventional salts with melting points below 100 °C. Apart from their negligible vapor pressure at room temperature, high thermal stability, and impressive solvation properties, ILs are characterized by their ...
Adrián Gutiérrez-Serpa, Patricia I. Napolitano-Tabares, Jakub Šulc, Idaira Pacheco-Fernández, Verónica Pino   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Movements of Magnetite-Encapsulated Graphene Particles at Air–Water Interface and Their Cell Growths under Dynamic Magnetic Field

Nanomaterials, 2023
The motion of magnetic particles under magnetic fields is an object to be solved in association with basic and practical phenomena. Movement phenomena of magnetite-encapsulated graphene particles at air–water interfaces were evaluated by manufacturing a ...
Jia Ji Lee, Misganu Chewaka Fite, Toyoko Imae, Poh Foong Lee   +3 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source