Results 81 to 90 of about 1,793,268 (362)

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

LISA improves statistical analysis for fMRI

Nature Communications, 2018
Functional magnetic resonance imaging (fMRI) is a powerful technique for measuring human brain activity, but the statistical analysis of fMRI data can be difficult.
Gabriele Lohmann, Johannes Stelzer, Eric Lacosse, Vinod J. Kumar, Karsten Mueller, Esther Kuehn, Wolfgang Grodd, Klaus Scheffler   +7 more
doaj   +1 more source

A Hitchhiker's Guide to Functional Magnetic Resonance Imaging

Frontiers in Neuroscience, 2016
Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular both with clinicians and researchers as they are capable of providing unique insights into brain functions.
J. Soares, R. Magalhães, P. Moreira, A. Sousa, E. Ganz, A. Sampaio, Victor Alves, P. Marques, N. Sousa   +8 more
semanticscholar   +1 more source

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He, Jie Wu, Chaonan Fan, Zheng Li, Jun Liu, Kechun Li, Quan Wang, Suyun Qian   +7 more
wiley   +1 more source

Radiomic Machine Learning in Invasive Ductal Breast Cancer: Prediction of Ki-67 Expression Level Based on Radiomics of DCE-MRI

Technology in Cancer Research & Treatment
Purpose Our study aimed to investigate the potential of radiomics with DCE-MRI for predicting Ki-67 expression in invasive ductal breast cancer. Method We conducted a retrospective study including 223 patients diagnosed with invasive ductal breast cancer.
Huan Yang MM, Wenxi Wang MM, Zhiyong Cheng MM, Tao Zheng MD, Cheng Cheng MD, Mengyu Cheng MM, Zhanqiu Wang MM   +6 more
doaj   +1 more source

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin   +10 more
wiley   +1 more source

Multiple diffusion metrics in differentiating solid glioma from brain inflammation

Frontiers in Neuroscience
Background and purposeThe differential diagnosis between solid glioma and brain inflammation is necessary but sometimes difficult. We assessed the effectiveness of multiple diffusion metrics of diffusion-weighted imaging (DWI) in differentiating solid ...
Kai Zhao, Ankang Gao, Eryuan Gao, Jinbo Qi, Ting Chen, Guohua Zhao, Gaoyang Zhao, Peipei Wang, Weijian Wang, Jie Bai, Yong Zhang, Huiting Zhang, Guang Yang, Xiaoyue Ma, Jingliang Cheng   +14 more
doaj   +1 more source

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents

International Journal of Nanomedicine, 2015
Magnetic resonance imaging (MRI) has become one of the most widely used and powerful tools for noninvasive clinical diagnosis owing to its high degree of soft tissue contrast, spatial resolution, and depth of penetration.
J. Estelrich, M. Sánchez-Martín, M. Busquets   +2 more
semanticscholar   +1 more source

Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji, Marcello Moccia, Alessia Bianchi, Charmaine Yam, Weaam Hamed, Suraya Mohamud, Alan J. Thompson, Frederik Barkhof, Ahmed T. Toosy, Olga Ciccarelli   +9 more
wiley   +1 more source

Individualized gray matter morphological abnormalities unveil two neuroanatomical obsessive-compulsive disorder subtypes

Translational Psychiatry
Obsessive-compulsive disorder (OCD) is a highly heterogeneous disorder, with notable variations among cases in structural brain abnormalities. To address this heterogeneity, our study aimed to delineate OCD subtypes based on individualized gray matter ...
Baohong Wen, Keke Fang, Qiuying Tao, Ya Tian, Lianjie Niu, Wenqing Shi, Zijun Liu, Jin Sun, Liang Liu, Xiaopan Zhang, Ruiping Zheng, Hui-Rong Guo, Yarui Wei, Yong Zhang, Jingliang Cheng, Shaoqiang Han   +15 more
doaj   +1 more source