Results 61 to 70 of about 4,231,048 (252)

Brain network construction and analysis for patients with mild cognitive impairment and Alzheimer's disease based on a highly‐available nodes approach

open access: yesBrain and Behavior, 2021
Introduction Using brain network and graph theory methods to analyze the Alzheimer's disease (AD) and mild cognitive impairment (MCI) abnormal brain function is more and more popular. Plenty of potential methods have been proposed, but the representative
Xiaopan Zhang   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Diagnostic utility of cardiac magnetic resonance-derived myocardial strain and fractal analysis in differentiating left ventricular noncompaction from dilated cardiomyopathy

open access: yesBMC Medical Imaging
Objective This study aimed to evaluate the diagnostic value of combining cardiac magnetic resonance (CMR) myocardial strain analysis with fractal analysis in differentiating left ventricular noncompaction (LVNC) from dilated cardiomyopathy (DCM). Methods
Yanan Jin   +4 more
doaj   +1 more source

Use of Nuclear Magnetic Resonance Imaging Angiography to Follow-Up Arterial Remodeling in an Animal Model [PDF]

open access: yes, 1998
Appropriately sized arteries in small animals may be possible models for studying the remodeling process as occurs after arterial balloon injury in humans. Magnetic resonance imaging (MRI) is able to noninvasively image tissue in vivo.
Schwaiger, Markus   +6 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Distance-related functional connectivity alterations in first-episode, drug-naïve major depressive disorder: a resting-state fMRI study with atlas-based neurotransmitter correlates

open access: yesBMC Psychiatry
Background Major depressive disorder (MDD) has been associated with large-scale functional dysconnectivity, yet it remains unclear whether these abnormalities differ as a function of anatomical distance.
Yuzhen Ding   +11 more
doaj   +1 more source

Development of a deep learning algorithm for detection of liver cancers on Magnetic Resonance Imaging

open access: yes, 2020
Early detection of liver cancer is crucial for improving patient management outcome. However, liver lesions can be differencaited to be identified. In recent years, the fully convolution neural network (FCNN) has shown to be able to achieve commensurate ...
Chiu, WHK   +4 more
core  

Imaging of Hepatocellular Carcinoma by Computed Tomography and Magnetic Resonance Imaging: State of the Art [PDF]

open access: yes, 2009
Hepatocellular carcinoma (HCC) is a very frequent tumor worldwide. Its incidence is linked to the distribution of liver cirrhosis and viral hepatitis, which are the main risk factors for the development of HCC.
Reiser, Maximilian F.   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Resting-state functional connectivity alterations in intermet gaming disorder: A fMRI study combining voxel-based morphometry meta-analysis

open access: yesBrain Research Bulletin
Background: Internet gaming disorder (IGD) is a behavioral addiction, as revealed by previous neuroimaging studies on gray matter volume alterations and functional connectivity abnormalities that patients with internet gaming disorder have.
Xinyu Wang   +10 more
doaj   +1 more source

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