Results 51 to 60 of about 4,231,048 (252)

Prognostic value of left ventricular structure and strain in chronic kidney disease patients by cardiovascular magnetic resonance imaging: a retrospective study [PDF]

open access: yesPeerJ
Background Individuals suffering from chronic kidney disease (CKD) frequently face a heightened likelihood of experiencing cardiovascular complications, including heart failure and cardiac mortality.
Wenju Zhang   +5 more
doaj   +2 more sources

Functional and Structural Magnetic Resonance Imaging of Humans and Macaques [PDF]

open access: yes, 2004
Magnetic resonance imaging (MRI) is a technique which finds use in the neurosciences both as an anatomical and functional localization tool. The traditional uses of MRI for structural analysis, such as are commonly found in medicine, can be adapted to ...
Bernheim, Kyle Alan
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The development and assessment of cardiac magnetic resonance imaging for the detection of age- and disease-related changes in the human heart [PDF]

open access: yes, 2013
Cardiovascular disease (CVD) is a term used to describe a variety of diseases and events that impact the heart and circulatory system. CVD is the United Kingdom’s (UKs) biggest killer, causing more than 50,000 premature deaths each year.
Matthew, Shona
core   +2 more sources

Abnormal effective connectivity of default mode network subsystems affects depressive symptoms and sleep disturbances in adolescents with internet gaming disorder

open access: yesBMC Psychiatry
Background Studies have demonstrated that Internet gaming disorder (IGD) was associated with sleep and psychological disorders. The default mode network (DMN) is not a unitary system, but rather is composed of smaller and distinct functional subsystems ...
Mengzhe Zhang   +7 more
doaj   +1 more source

Altered Resting-State Functional Connectivity in Internet Gaming Disorder: Convergent Evidence and Independent Validation

open access: yesAddictive Behaviors Reports
Background: Internet gaming disorder (IGD) has attracted increasing attention worldwide. However, findings from resting-state functional connectivity (RSFC) studies have remained inconsistent, making it difficult to identify robust and reproducible ...
Jiawen Tian   +11 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Altered functional connectivity within the primary visual networks and neurotransmitter activity in male smokers: A group ICA study

open access: yesBrain Research Bulletin
Smoking puts patients at high risk for cognitive and psychiatric disorders. The aim of this study was to explore the effects of nicotine use on primary visual network (PVN) and its association with neurotransmitters.
Jieping Sun   +12 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Static and temporal dynamic changes of intrinsic brain activity in early-onset and adult-onset schizophrenia: a fMRI study of interaction effects

open access: yesFrontiers in Neurology
BackgroundSchizophrenia is characterized by altered static and dynamic spontaneous brain activity. However, the conclusions regarding this are inconsistent.
Jingli Chen   +17 more
doaj   +1 more source

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