Results 51 to 60 of about 1,628,480 (298)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Optimizing hip MRI: enhancing image quality and elevating inter-observer consistency using deep learning-powered reconstruction

BMC Medical Imaging
Background Conventional hip joint MRI scans necessitate lengthy scan durations, posing challenges for patient comfort and clinical efficiency. Previously, accelerated imaging techniques were constrained by a trade-off between noise and resolution ...
Yimeng Kang, Wenjing Li, Qingqing Lv, Qiuying Tao, Jieping Sun, Jinghan Dang, Xiaoyu Niu, Zijun Liu, Shujian Li, Zanxia Zhang, Kaiyu Wang, Baohong Wen, Jingliang Cheng, Yong Zhang, Weijian Wang   +14 more
doaj   +1 more source

The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis

Frontiers in Psychiatry
BackgroundWhile numerous previous studies have indicated that nicotine intake results in gray matter and functional brain abnormalities in tobacco use disorder (TUD), the majority of results could not be replicated or even reversed.
Longyao Ma, Longyao Ma, Qiuying Tao, Qiuying Tao, Jinghan Dang, Jinghan Dang, Jieping Sun, Jieping Sun, Xiaoyu Niu, Xiaoyu Niu, Mengzhe Zhang, Mengzhe Zhang, Yimeng Kang, Yimeng Kang, Weijian Wang, Weijian Wang, Jingliang Cheng, Jingliang Cheng, Yong Zhang, Yong Zhang   +19 more
doaj   +1 more source

Evaluation of left ventricular blood flow kinetic energy in patients with acute myocardial infarction by 4D Flow MRI: a preliminary study

BMC Medical Imaging
Purpose To evaluate the intracavity left ventricular (LV) blood flow kinetic energy (KE) parameters using four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) in patients with acute myocardial infarction (AMI).
Xiqing Niu, Yutong Dun, Guoce Li, Houning Zhang, Bin Zhang, Zhibin Pan, Hao Bian, Liqing Kang, Fenghai Liu   +8 more
doaj   +1 more source

Optimization of the acceleration of compressed sensing in whole-heart contrast-free coronary magnetic resonance angiography

Journal of Cardiovascular Magnetic Resonance
: Background: This study aims to identify optimal acceleration factors (AFs) for compressed sensing (CS) technology to enhance its clinical application for suspected coronary artery disease (CAD) in whole-heart non-contrast coronary magnetic resonance ...
Weiwei Wang, Longyan Zhang, Guangzong Su, Feng Xiong, Yang Wu, Ke Yu, Qiaodan Yi, Peng Sun   +7 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Altered intrinsic neural activity and its molecular analyses in first-episode schizophrenia with auditory verbal hallucinations

Frontiers in Neuroscience
BackgroundAuditory verbal hallucinations (AVHs) are one of the signature positive symptoms of schizophrenia, affecting a substantial portion of patients with schizophrenia.
Ziyu Wang, Ziyu Wang, Kangkang Xue, Kangkang Xue, Yimeng Kang, Yimeng Kang, Zijun Liu, Zijun Liu, Jingliang Cheng, Jingliang Cheng, Yan Zhang, Yan Zhang, Yarui Wei, Yarui Wei   +13 more
doaj   +1 more source

The Evaluation of Zoomed Echo-Planar Diffusion-Weighted Magnetic Resonance Imaging With Two-dimensional Spatial-Selective Radiofrequency Excitation Pulses in Patients With Hilar Cholangiocarcinoma

Frontiers in Oncology, 2022
BackgroundWe aimed to investigate the feasibility and application of using the zoomed diffusion-weighted echo-planar imaging (z-EPI DWI) sequences for hilar cholangiocarcinoma assessment compared with conventional single-shot EPI diffusion-weighted ...
Jingjing Liu, Mengyue Huang, Yanan Ren, Man Xu, Yinhua Li, Jingliang Cheng, Jinxia Zhu   +6 more
doaj   +1 more source

Nuclear Magnetic Resonance Imaging of Li-ion Battery [PDF]

, 2010
Nuclear magnetic resonance (NMR) imaging has high sensitivity to proton (1H) and lithium (7Li). It is a useful measurement for electrolyte in Li-ion battery. 1H NMR images of lithium ion battery which is composed of LiMn2O4 / LiClO4 + propylene carbonate
Iwai, Y. (Y), Kawamura, J. (J), Ohno, D. (D)   +2 more
core  

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source