Results 21 to 30 of about 202,156 (302)

Programmable macrophage-polarizing nanoparticles for MRI-guided early detection and treatment of pulmonary metastases

Journal of Nanobiotechnology
Metastatic lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the urgent need for early detection and intervention strategies.
Meiju Sui, Kairu Xie, Yingying Luo, Haiqiang Wang, Hao Sheng, Sen Yue, Xiaoxun Liu, Sha Li, Jung Soo Suk, Shizhen Chen, Daiqin Chen, Xin Zhou   +11 more
doaj   +1 more source

MRI-traceable Nanoenzyme for Cascade Catalysis-enhanced Immunotherapy

Chinese Journal of Magnetic Resonance
The immunosuppressive tumor microenvironment (ITME) poses a significant challenge to anti-tumor immunotherapy. Our research develops a novel nanoenzyme based on Mn2+ and endogenous hemin.
SUI Meiju, ZHANG Lei, WANG Ruifang, LUO Yingying, LI Sha, QIU Maosong, XU Qiuyi, CHEN Daiqin, CHEN Shizhen, ZHOU Xin   +9 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Effects of Seizure-inducing Doses Nicotine on Hippocampal Structure in Adolescent Female Rats

Chinese Journal of Magnetic Resonance
In recent years, there have been frequent cases of seizures among adolescents after using e-cigarettes, which has aroused deep concern about the potential health risks of excessive nicotine intake.
CHEN Xi, LIU Sijie, CAI Yue, CHENG Linlin, WANG Xuxia, KANG Yan, LIN Fuchun, LEI Hao   +7 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Magnetic Resonance Spectroscopy

Klinicheskaia laboratornaia diagnostika, 2002
Life-time diagnosis of the initial pathological shifts in the organism remains an and still unsolved important problem of modern medicine. Magnetic resonance spectroscopy based on the nuclear magnetic resonance phenomenon is one of the methods which can help to solve this problem.
Stephen Williams, Nicola Sibson
openaire   +3 more sources

NMR-guided rational exploration of co-factors in boosting the Pfu DNA polymerase

Magnetic Resonance Letters
With rapid developments of emerging technologies like synthetic biology, the demand for DNA polymerases with superior activities including higher thermostability and processivity has increased significantly. Thus, rational optimization of the performance
Yihao Chen, Mingjun Zhu, Ruishen Ding, Xiaoling Zhao, Zhiqing Tao, Xu Zhang, Maili Liu, Lichun He   +7 more
doaj   +1 more source

Phosphorus Magnetic Resonance Spectroscopy (31P MRS) and Cardiovascular Disease: The Importance of Energy [PDF]

, 2023
Vasiliki Tsampasian, Donnie Cameron, Rashed Sobhan, George Bazoukis, Vassilios S. Vassiliou   +4 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation

Nature Communications
Orderly development of neuroendocrine and nervous system of mammals requires INSM1, a key regulator for cell differentiation. Ectopic expression of INSM1 is closely correlated with human neuroendocrine tumorigenesis, which makes INSM1 a reliable ...
Heng Zhou, Xiaoling He, Yue Xiong, Yixuan Gong, Yuanyuan Zhang, Shuangli Li, Rui Hu, Ying Li, Xu Zhang, Xin Zhou, Jiang Zhu, Yunhuang Yang, Maili Liu   +12 more
doaj   +1 more source