Results 31 to 40 of about 3,223,690 (300)

Magnetic resonance spectroscopy in the evaluation of treatment efficacy in unipolar major depressive disorder: a review of the literature [PDF]

, 2012
More and more neuroimaging studies are using in vivo proton magnetic resonance spectroscopy (1H-MRS) to explore correlates of response to therapy in major depressive disorder (MDD). Their aim is to further understanding of the effects of neurotransmitter
Barale, Francesco, Pichiecchio, Anna, Biondi, Massimo, Pasin, Marino, Palesi, Fulvia, Castellazzi, Gloria, Caverzasi, Edoardo, Calligaro, Alessandro, Pasquini, Massimo, Poloni, Guy, Bastianello, Stefano   +10 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Unveiling the thermodynamic-kinetic trade-off effect on acid sites in zeolite-catalyzed alcohol dehydration

Nature Communications
Understanding the distinct roles of Brønsted and Lewis acid sites remains a great challenge in designing zeolite catalysts, as their coexistence often obscures mechanistic understanding.
Min Hu, Yueying Chu, Chao Wang, Wenjin Cai, Qiang Wang, Jun Xu, Feng Deng   +6 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Programmable macrophage-polarizing nanoparticles for MRI-guided early detection and treatment of pulmonary metastases

Journal of Nanobiotechnology
Metastatic lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the urgent need for early detection and intervention strategies.
Meiju Sui, Kairu Xie, Yingying Luo, Haiqiang Wang, Hao Sheng, Sen Yue, Xiaoxun Liu, Sha Li, Jung Soo Suk, Shizhen Chen, Daiqin Chen, Xin Zhou   +11 more
doaj   +1 more source

MRI-traceable Nanoenzyme for Cascade Catalysis-enhanced Immunotherapy

Chinese Journal of Magnetic Resonance
The immunosuppressive tumor microenvironment (ITME) poses a significant challenge to anti-tumor immunotherapy. Our research develops a novel nanoenzyme based on Mn2+ and endogenous hemin.
SUI Meiju, ZHANG Lei, WANG Ruifang, LUO Yingying, LI Sha, QIU Maosong, XU Qiuyi, CHEN Daiqin, CHEN Shizhen, ZHOU Xin   +9 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Nuclear magnetic resonance spectroscopy and computational methods for the characterization of materials in solution and the solid state [PDF]

, 2010
Nuclear Magnetic Resonance (NMR) and computational methods increasingly play a predominant and indispensable role in modern chemical research. The insights into the local nuclear environment that NMR can provide is unique information which allows the ...
Carnevale, Diego
core   +2 more sources

Effects of Seizure-inducing Doses Nicotine on Hippocampal Structure in Adolescent Female Rats

Chinese Journal of Magnetic Resonance
In recent years, there have been frequent cases of seizures among adolescents after using e-cigarettes, which has aroused deep concern about the potential health risks of excessive nicotine intake.
CHEN Xi, LIU Sijie, CAI Yue, CHENG Linlin, WANG Xuxia, KANG Yan, LIN Fuchun, LEI Hao   +7 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source