Results 21 to 30 of about 193,499 (166)

Magnetic Resonance Spectroscopy

Science Progress, 2017
Since the original observation by Zeeman, that spectral lines can be affected by magnetic fields, ‘magnetic spectroscopy’ has evolved into the broad arsenal of techniques known as ‘magnetic resonance’. This review focuses on nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), and muon spin resonance (μSR): methods which have ...
openaire   +2 more sources

Multivariate metal-organic frameworks enable chemical shift-encoded MRI with femtomolar sensitivity for biological systems

Nature Communications
Fluorescent molecules with specific target moieties are essential for histopathological analysis, but their limited tissue penetration depth makes in vivo, in situ color encoding analysis challenging.
Qingbin Zeng, Quer Yue, Ming Zhang, Rui Zhou, Zhen Wang, Zhongyu Xiao, Yaping Yuan, Xiuchao Zhao, Weiping Jiang, Lei Zhang, Yuqi Yang, Minghui Yang, Haidong Li, Louis-S. Bouchard, Qianni Guo, Xin Zhou   +15 more
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Development and Applications of HDX-NMR and HDX-MS in Protein Structure and Dynamics Research

Chinese Journal of Magnetic Resonance
Hydrogen-deuterium exchange nuclear magnetic resonance (HDX-NMR) and hydrogen-deuterium exchange mass spectrometry (HDX-MS) are key techniques for studying protein structure and dynamics, and have been widely applied to analyzing protein conformational ...
ZHANG Yuanyuan, WANG Pengcheng, LI Tao, HU Rui, YANG Yunhuang, LIU Maili   +5 more
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Unveiling the thermodynamic-kinetic trade-off effect on acid sites in zeolite-catalyzed alcohol dehydration

Nature Communications
Understanding the distinct roles of Brønsted and Lewis acid sites remains a great challenge in designing zeolite catalysts, as their coexistence often obscures mechanistic understanding.
Min Hu, Yueying Chu, Chao Wang, Wenjin Cai, Qiang Wang, Jun Xu, Feng Deng   +6 more
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Programmable macrophage-polarizing nanoparticles for MRI-guided early detection and treatment of pulmonary metastases

Journal of Nanobiotechnology
Metastatic lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the urgent need for early detection and intervention strategies.
Meiju Sui, Kairu Xie, Yingying Luo, Haiqiang Wang, Hao Sheng, Sen Yue, Xiaoxun Liu, Sha Li, Jung Soo Suk, Shizhen Chen, Daiqin Chen, Xin Zhou   +11 more
doaj   +1 more source

MRI-traceable Nanoenzyme for Cascade Catalysis-enhanced Immunotherapy

Chinese Journal of Magnetic Resonance
The immunosuppressive tumor microenvironment (ITME) poses a significant challenge to anti-tumor immunotherapy. Our research develops a novel nanoenzyme based on Mn2+ and endogenous hemin.
SUI Meiju, ZHANG Lei, WANG Ruifang, LUO Yingying, LI Sha, QIU Maosong, XU Qiuyi, CHEN Daiqin, CHEN Shizhen, ZHOU Xin   +9 more
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Effects of Seizure-inducing Doses Nicotine on Hippocampal Structure in Adolescent Female Rats

Chinese Journal of Magnetic Resonance
In recent years, there have been frequent cases of seizures among adolescents after using e-cigarettes, which has aroused deep concern about the potential health risks of excessive nicotine intake.
CHEN Xi, LIU Sijie, CAI Yue, CHENG Linlin, WANG Xuxia, KANG Yan, LIN Fuchun, LEI Hao   +7 more
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NMR-guided rational exploration of co-factors in boosting the Pfu DNA polymerase

Magnetic Resonance Letters
With rapid developments of emerging technologies like synthetic biology, the demand for DNA polymerases with superior activities including higher thermostability and processivity has increased significantly. Thus, rational optimization of the performance
Yihao Chen, Mingjun Zhu, Ruishen Ding, Xiaoling Zhao, Zhiqing Tao, Xu Zhang, Maili Liu, Lichun He   +7 more
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Sustained Release of Co-Amorphous Matrine-Type Alkaloids and Resveratrol with Anti-COVID-19 Potential

Pharmaceutics, 2022
Matrine (MAR), oxymatrine (OMAR), and sophoridine (SPD) are natural alkaloids with varying biological activities; matrine was recently used for the treatment of coronavirus disease 2019 (COVID-19).
Dandan Hu, Xin Chen, Duanxiu Li, Hailu Zhang, Yanwen Duan, Yong Huang   +5 more
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Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation

Nature Communications
Orderly development of neuroendocrine and nervous system of mammals requires INSM1, a key regulator for cell differentiation. Ectopic expression of INSM1 is closely correlated with human neuroendocrine tumorigenesis, which makes INSM1 a reliable ...
Heng Zhou, Xiaoling He, Yue Xiong, Yixuan Gong, Yuanyuan Zhang, Shuangli Li, Rui Hu, Ying Li, Xu Zhang, Xin Zhou, Jiang Zhu, Yunhuang Yang, Maili Liu   +12 more
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