Results 21 to 30 of about 3,434,501 (302)

Magnetic resonance spectroscopy in the evaluation of treatment efficacy in unipolar major depressive disorder: a review of the literature [PDF]

, 2012
More and more neuroimaging studies are using in vivo proton magnetic resonance spectroscopy (1H-MRS) to explore correlates of response to therapy in major depressive disorder (MDD). Their aim is to further understanding of the effects of neurotransmitter
Barale, Francesco, Pichiecchio, Anna, Biondi, Massimo, Pasin, Marino, Palesi, Fulvia, Castellazzi, Gloria, Caverzasi, Edoardo, Calligaro, Alessandro, Pasquini, Massimo, Poloni, Guy, Bastianello, Stefano   +10 more
core   +1 more source

Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR [PDF]

, 2015
AG acknowledges a postgraduate fellowship by the EPSRC funded doctoral training centre ‘integrated magnetic resonance’. BEB is grateful for an EaStCHEM Hirst Academic Fellowship by the School of Chemistry, St Andrews, and funding from the People ...
Bode, Bela Ernest, Slawin, Alexandra Martha Zoya, Giannoulis, A., Cordes, D. B., Ackermann, K., Ackermann, Katrin, Giannoulis, Angeliki, Cordes, David Bradford, Slawin, A. M. Z., Bode, B. E., Slawin, Alexandra Martha Zoya; id_orcid, Bode, Bela Ernest; id_orcid, Cordes, David Bradford; id_orcid, Ackermann, Katrin; id_orcid, Ackermann, K.; id_orcid, Cordes, D. B.; id_orcid, Bode, B. E.; id_orcid, Slawin, A. M. Z.; id_orcid   +17 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Multivariate metal-organic frameworks enable chemical shift-encoded MRI with femtomolar sensitivity for biological systems

Nature Communications
Fluorescent molecules with specific target moieties are essential for histopathological analysis, but their limited tissue penetration depth makes in vivo, in situ color encoding analysis challenging.
Qingbin Zeng, Quer Yue, Ming Zhang, Rui Zhou, Zhen Wang, Zhongyu Xiao, Yaping Yuan, Xiuchao Zhao, Weiping Jiang, Lei Zhang, Yuqi Yang, Minghui Yang, Haidong Li, Louis-S. Bouchard, Qianni Guo, Xin Zhou   +15 more
doaj   +1 more source

Research on Large-bore and High Homogeneity Halbach Magnet for Nuclear Magnetic Resonance

Chinese Journal of Magnetic Resonance
Halbach permanent magnets hold significant promise for low-field nuclear magnetic resonance (LF-NMR) applications, such as rock core analysis, owing to their yoke-free design and low external stray fields. Compared with small rock cores, large rock cores
LIU Wanzhen, CHEN Fang, CHEN Li, WANG Jiaxin, CHENG Xin, YI Peng, ZHANG Zhi, LIU Chaoyang   +7 more
doaj   +1 more source

Cardiovascular magnetic resonance activity in the United Kingdom: a survey on behalf of the british society of cardiovascular magnetic resonance [PDF]

, 2011
<p>Background: The indications, complexity and capabilities of cardiovascular magnetic resonance (CMR) have rapidly expanded. Whether actual service provision and training have developed in parallel is unknown.</p> <p>Methods: We ...
J. Moon (6723125), Pennell, D.J., S. Neubauer (1410220), Payne, J., J. Payne (2409088), Antony Renjith, Dargie, HJ, G. P. McCann (7591697), Antony, R, Hawkins, N.M., Payne John, C. Berry (7606274), Dargie, H.J., Renjith Antony, Nathaniel M Hawkins, Henry J Dargie, James Moon, Petrie Mark C, S. Daghem (7606259), Gerry P. McCann (7241615), Moon, J., Daghem, M., Pennell, DJ, Pennell Dudley J, Mark C Petrie, H. J. Dargie (7606265), Neubauer Stefan, Marwa Daghem, Antony, R., Gerry P McCann, R. Antony (7606253), McCann, GP, M. Daghem (7606256), Petrie, M.C., Moon James, Hawkins, NM, Safa Daghem, Daghem Marwa, Berry Colin, Colin Berry, D. J. Pennell (7606268), Dargie Henry J, McCann, G.P., Daghem, S, Payne, J, Neubauer, S., Hawkins Nathaniel M, Daghem, M, Daghem, S., Petrie, MC, McCann Gerry P, N. M. Hawkins (7606271), Moon, J, Dudley J Pennell, Berry, C, Berry, C., Neubauer, S, John Payne, M. C. Petrie (7606262), Daghem Safa, Stefan Neubauer   +60 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Development and Applications of HDX-NMR and HDX-MS in Protein Structure and Dynamics Research

Chinese Journal of Magnetic Resonance
Hydrogen-deuterium exchange nuclear magnetic resonance (HDX-NMR) and hydrogen-deuterium exchange mass spectrometry (HDX-MS) are key techniques for studying protein structure and dynamics, and have been widely applied to analyzing protein conformational ...
ZHANG Yuanyuan, WANG Pengcheng, LI Tao, HU Rui, YANG Yunhuang, LIU Maili   +5 more
doaj   +1 more source

13C Chemical Shift Assignment of Solid 2-Picolinic Acid by DFT/Crystallography Integrated Approach

Chinese Journal of Magnetic Resonance, 2020
The tautomerism of organic molecules is widely observed in solution. While for solid organic chemicals, molecules often exist in the most stable tautomeric form.
ZHANG Zhi-jie, LI Duan-xiu, LUO Chun, QIU Ru-chen, DENG Zong-wu, ZHANG Hai-lu   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source