Results 41 to 50 of about 519,038 (293)

Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation

Nature Communications
Orderly development of neuroendocrine and nervous system of mammals requires INSM1, a key regulator for cell differentiation. Ectopic expression of INSM1 is closely correlated with human neuroendocrine tumorigenesis, which makes INSM1 a reliable ...
Heng Zhou, Xiaoling He, Yue Xiong, Yixuan Gong, Yuanyuan Zhang, Shuangli Li, Rui Hu, Ying Li, Xu Zhang, Xin Zhou, Jiang Zhu, Yunhuang Yang, Maili Liu   +12 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

19F NMR study of proteins with parallel incorporation of multiple fluorinated aromatic amino acids

Magnetic Resonance Letters
Although the parallel incorporation of fluorinated aromatic amino acids (FAAAs) into proteins has been explored since 2010, the corresponding 19F NMR investigation has been lacking to date.
Manman Li, Guohua Xu, Qiong Wu, Ling Jiang, Conggang Li   +4 more
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Research on a Multi-modal Enhanced Denoising Diffusion Model for Hyperpolarized 129Xe MRI

Chinese Journal of Magnetic Resonance
Hyperpolarized 129Xe magnetic resonance imaging (MRI) is an emerging medical imaging technique that plays an important role in the diagnosis and treatment of numerous lung diseases.
ZHANG Mingyu, XIAO Sa, SHI Shengjie, ZHANG Xuecheng, ZHOU Xin   +4 more
doaj   +1 more source

Cognitive-behavioral therapy for obsessive-compulsive disorder: access to treatment, prediction of long-term outcome with neuroimaging. [PDF]

, 2015
This article reviews issues related to a major challenge to the field for obsessive-compulsive disorder (OCD): improving access to cognitive-behavioral therapy (CBT).
Feusner, Jamie D, O'Neill, Joseph
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Unexpected temperature dependence of 1H paramagnetic shift in MAS NMR of nickelocene

Magnetic Resonance Letters
This work revisits the temperature dependence of 1H paramagnetic shift in nickelocene as a potential nuclear magnetic resonance (NMR) thermometer under fast magic angle spinning (MAS) rate.
Xinbiao Jiang, Jiefan Liu, Xiaobing Lou, Bingwen Hu, Ming Shen   +4 more
doaj   +1 more source

Qualitative and quantitative analysis of mixtures of compounds containing both hydrogen and deuterium [PDF]

, 1969
Method allows qualitative and quantitative analysis of mixtures of partially deuterated compounds. Nuclear magnetic resonance spectroscopy determines location and amount of deuterium in organic compounds but not fully deuterated compounds.
Crespi, H. L., Harkness, L., Katz, J. J., Norman, G., Saur, W.   +4 more
core   +1 more source

Manifold Learning in MR spectroscopy using nonlinear dimensionality reduction and unsupervised clustering [PDF]

, 2014
Purpose To investigate whether nonlinear dimensionality reduction improves unsupervised classification of 1H MRS brain tumor data compared with a linear method. Methods In vivo single-voxel 1H magnetic resonance spectroscopy (55 patients) and 1H magnetic
Barrick, TR, Howe, FA, Raschke, F, Yang, G   +3 more
core   +1 more source