Results 61 to 70 of about 4,456,010 (385)

Highly sensitive chemiluminescent aptasensor for detecting HBV infection based on rapid magnetic separation and double-functionalized gold nanoparticles

Scientific Reports, 2018
Hepatitis B virus (HBV) infection is a major global public health problem and one of the leading causes of chronic liver disease. HBsAg is the first serological marker to appear in the blood and is the most important marker of HBV infection. Detection of
Zhijiang Xi, Q. Gong, Chao Wang, Bing Zheng   +3 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Magnetic separation of ash and slag residues for their multi-component utilization: An overview

International Journal of Coal Science & Technology
Over the last decades, huge amounts of ash residues have been generated worldwide leading to increasing demand for viable recycling technologies. Magnetic separation is considered a promising option for sustainable management of these wastes. The present
Lucie Bartoňová, Filip Kovár, Marek Kucbel   +2 more
doaj   +1 more source

Magnetic separation of titanium-containing minerals

Vestnik MGTU, 2019
The studies have been carried out on the Afrikanda (the Murmansk region) titanium-containing minerals segregation by magnetic separation. The technological scheme of ore preparation and further enrichment is developed taking into account the ...
Andronov G. P., Filimonova N. M., Khokhulya M. S.   +2 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Average motion of emerging solar active region polarities I: Two phases of emergence

, 2019
Our goal is to constrain models of active region formation by tracking the average motion of active region polarity pairs as they emerge onto the surface.
Birch, Aaron C., Braun, Douglas C., Burston, Raymond B., Cameron, Robert H., Gizon, Laurent, Schunker, Hannah   +5 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Glassy magnetic phase driven by short range charge and magnetic ordering in nanocrystalline La$_{1/3}$Sr$_{2/3}$FeO$_{3-\delta}$: Magnetization, Mossbauer, and polarised neutron studies [PDF]

, 2012
The charge ordered La$_{1/3}$Sr$_{2/3}$FeO$_{3-\delta}$ (LSFO) in bulk and nanocrystalline forms are investigated using ac and dc magnetization, M\"{o}ssbauer, and polarised neutron studies.
Amaral, V. S., Borghols, W., Chatterji, T., Das, S., Giri, S., Iglesias, O., Majumdar, S., Patra, M., Sabyasachi, Sk.   +8 more
core   +4 more sources

Study on the whole-grain magnetic–float combination beneficiation process of high mud lithium mica

工程科学学报
The South China region is abundant in high mud lithium mica resources, which are characterized by their complex mineral composition and high fine mud content.
Rongrui WANG, Yongbiao CHENG, Junhao FU, Haisheng HAN, Jie DING, Jianhua KANG, Yong LI   +6 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source