Results 141 to 150 of about 66,879 (258)

Hyperviscosity‐Related Ischemic Stroke in an Adolescent With Unrepaired Tetralogy of Fallot: A Case Report From a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Chronic hypoxemia in uncorrected TOF causes compensatory erythrocytosis and hyperviscosity, predisposing to cerebrovascular complications. Stroke in this context is rare but clinically significant, especially in resource‐limited settings where access to imaging and
Ayenew A. Wolie, Chernet T. Mengistie, Biruk T. Mengistie, Elleni D. Mulatu, Rahel N. Teferi, Birhanu T. Andeta, Gedefaw T. Minwagaw   +6 more
wiley   +1 more source

Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging

Journal of Magnetic Resonance Imaging, Volume 63, Issue 4, Page 917-937, April 2026.
ABSTRACT MRI of the heart and abdominal organs provides unparalleled soft tissue contrast and quantitative biomarkers, yet remains highly susceptible to physiological motion. Contractions of the myocardium, respiratory excursions, peristalsis, vascular pulsatility, and unpredictable bulk patient movement generate artifacts that impair image quality ...
Eric M. Schrauben, Gastao Lima da Cruz, Christopher W. Roy, Thomas Küstner   +3 more
wiley   +1 more source

Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song, Lin Yuan, Weiguo Yang, Wen Li, Jia‐Yi Li   +4 more
wiley   +1 more source

Human CNTNAP1 Variants Associated With Severe Neurological Deficits: Additional Cases and Literature Review

Muscle &Nerve, Volume 73, Issue 4, Page 517-526, April 2026.
ABSTRACT CNTNAP1 encodes the Contactin‐Associated Protein 1 (CNTNAP1), also known as Caspr1, which is a transmembrane protein critical for nervous system function. CNTNAP1 is localized to the paranodal regions of all myelinated axons, flanking either side of the node of Ranvier.
Lacey B. Sell, Derek Garcia, Alexandra Hollá, Ilana Chilton, Seth DeVries, Ana María Gómez‐Moreno, Manuel Lubián‐Gutiérrez, Qian Shi, Manzoor A. Bhat   +8 more
wiley   +1 more source

Lymphatic topology reveals a novel intranodal lympho‐venous shunt

The Journal of Pathology, Volume 268, Issue 4, Page 477-492, April 2026.
Abstract Understanding the lymphatic network is crucial for immunological research. Currently, a complete map of lymphatic drainage in mice is lacking. We present a detailed lymphatic system flow dynamic of two mouse strains with swollen lymph nodes (LNs), using region‐specific tracer injection and high‐resolution micro‐CT imaging to characterize LN ...
Ariunbuyan Sukhbaatar, Radhika Mishra, Akira Nakamura, Shiro Mori, Tsuyoshi Sugiura, Tetsuya Kodama   +5 more
wiley   +1 more source

Right Atrial Thrombus in Transit: A Case of Spontaneous Embolisation Captured Across Echocardiography

Respirology Case Reports, Volume 14, Issue 4, April 2026.
In this report, we describe a large RA thrombus in transit captured sequentially across multiple imaging modalities. This case highlights how quickly these thrombi can evolve and emphasises the need for individualised decision‐making when standard interventions are limited by clinical context.
Abdullah Al Qaraghuli, Sajjad Ghanim Al‐Badri, Mustafa Kadhim, Tala A. Haddad, Ronald Cadillo Hernandez, Sai Nitya Tejaswi Anne, Sashank Bollu, Ibrahim Khalil   +7 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Ventriculoperitoneal shunt-associated cystic lesion with perilesional cerebral edema 45 years after placement for posterior fossa tumor: A case report. [PDF]

Surg Neurol Int
Sato K, Hatae R, Otsuji R, Mukae N, Fujioka Y, Kuga D, Yamashita K, Yoshimoto K.   +7 more
europepmc   +1 more source

Shunt surgery and lecanemab therapy in patients with idiopathic normal pressure hydrocephalus and alzheimer's disease: a report of two cases. [PDF]

Acta Neurochir (Wien)
Miyazaki K, Morita H, Ishii K.
europepmc   +1 more source

Bilateral dynamic cerebral autoregulation assessment during endovascular treatment in large‐vessel occlusion stroke

Experimental Physiology, Volume 111, Issue 4, Page 2348-2369, 1 April 2026.
Abstract Recanalization by endovascular treatment (EVT) is effective in acute ischaemic stroke caused by large‐vessel occlusion. Better understanding of the pathophysiology could possibly identify targets for improving peri‐procedural management and thereby patient outcome.
Adam Vittrup Heiberg, Troels Gil Lukassen, Thomas Clement Truelsen, Henrik Gutte Borgwardt, Goetz Benndorf, Christine Sølling, Henrik Winther Schytz, Klaus Hansen, Kirsten Møller, Helle Klingenberg Iversen   +9 more
wiley   +1 more source